Maternal gestational weight gain (GWG) and rapid infant weight gain in the first months of life are important determinants of a child's life-long rik of obesity. Maternal GWG has been associated with both rapid infant weight gain and the child's later development of insulin resistance, hypertension, and obesity. It is particularly important to improve these outcomes in the Latino population, where rates of obesity are higher than the general population. The proposed study (entitled GROW Baby) will create a new cohort of Latina women who are already enrolled in a randomized behavioral intervention to prevent preschool obesity and subsequently become pregnant during the study period. The Growing Right Onto Wellness trial (GROW) has enrolled 610 maternal- preschool child pairs (ages 3-5). The intervention teaches a behavioral toolkit focused on healthy nutrition, physical activity, media use, and sleep for both mother and child. The control condition is a school readiness program. By developing this new cohort of Latina women who become pregnant during the study period, the proposed research aims to test how behavioral interventions delivered before and during pregnancy support healthy maternal GWG and healthy infant growth. A committed primary mentor and a multi-disciplinary team of co-mentors will oversee the candidate's progression to becoming an independently funded physician scientist with a focus on improving health outcomes related to obesity in families, particularly those from the Latino community. The career development plan consists of advanced coursework in community-engaged research methodology and participation in 1) an ongoing behavioral intervention; 2) community engagement activities; and 3) local and national conferences. This mentored career award integrates a research strategy that advances pediatric obesity prevention during pregnancy with a career development plan that applies community engaged research methodology to behavioral interventions. Through the conduct of the proposed research, the candidate will advance the field of pediatric obesity prevention by understanding how a behavioral intervention implemented before and during pregnancy could support healthy weight for both mother and child.

Public Health Relevance

Obesity prevention must begin in pregnancy, a period of childhood development ripe for effective interventions. This study will test whether a family-based, community centered behavioral intervention delivered prior to conception and during pregnancy will support healthy pregnancy weight gain and healthy infant growth. Only by amplifying obesity prevention to the level of the family can we hope to address the expanding public health crisis of pediatric obesity.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
6K23HL127104-02
Application #
9285948
Study Section
NHLBI Mentored Patient-Oriented Research Review Committee (MPOR)
Program Officer
Pratt, Charlotte
Project Start
2016-01-01
Project End
2020-12-31
Budget Start
2016-06-10
Budget End
2016-12-31
Support Year
2
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
DUNS #
079917897
City
Nashville
State
TN
Country
United States
Zip Code
37232
Heerman, William J; Burgess, Laura E; Escarfuller, Juan et al. (2018) Competency Based Approach to Community Health (COACH): The methods of a family-centered, community-based, individually adaptive obesity randomized trial for pre-school child-parent pairs. Contemp Clin Trials 73:1-7
Heerman, William J; Berge, Jerica M; Barkin, Shari L (2018) Mentoring of Early-Stage Investigators When Funding Is Tight: The Childhood Obesity Prevention and Treatment Research Experience. JAMA Pediatr 172:4-6
Teeters, Leah A; Heerman, William J; Schlundt, David et al. (2018) Community readiness assessment for obesity research: pilot implementation of the Healthier Families programme. Health Res Policy Syst 16:2
Heerman, William J; Schludnt, David; Harris, Dawn et al. (2018) Scale-out of a community-based behavioral intervention for childhood obesity: pilot implementation evaluation. BMC Public Health 18:498
Heerman, William J; Lounds-Taylor, Julie; Mitchell, Stephanie et al. (2018) Validity of the toddler feeding questionnaire for measuring parent authoritative and indulgent feeding practices which are associated with stress and health literacy among Latino parents of preschool children. Nutr Res 49:107-112
Barkin, Shari L; Heerman, William J; Sommer, Evan C et al. (2018) Effect of a Behavioral Intervention for Underserved Preschool-Age Children on Change in Body Mass Index: A Randomized Clinical Trial. JAMA 320:450-460
Fletcher, Grace E; Teeters, Leah; Schlundt, David et al. (2018) Maternal conception of gestational weight gain among Latinas: A qualitative study. Health Psychol 37:132-138
Heerman, William J; JaKa, Meghan M; Berge, Jerica M et al. (2017) The dose of behavioral interventions to prevent and treat childhood obesity: a systematic review and meta-regression. Int J Behav Nutr Phys Act 14:157
Heerman, William J; Jackson, Natalie; Hargreaves, Margaret et al. (2017) Clusters of Healthy and Unhealthy Eating Behaviors Are Associated With Body Mass Index Among Adults. J Nutr Educ Behav 49:415-421.e1
JaKa, M M; Haapala, J L; Trapl, E S et al. (2016) Reporting of treatment fidelity in behavioural paediatric obesity intervention trials: a systematic review. Obes Rev 17:1287-1300

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