Career Development Plan: The applicant is requesting 5 years of funding through the Mentored Patient- Oriented Research Career Development Award (K23-PA-05-143) to develop her into an independent investigator in HIV/AIDS health disparities research, with an emphasis on investigating the sociocultural aspects of antiretroviral adherence and biologic outcomes with HIV+ Hispanics. Career Development Methods: A coordinated, mentored curriculum of didactic and research training and study development is proposed. Dr. Rivera Mindt will receive guidance from her mentors;will complete formal coursework and training in sociocultural and adherence research, HIV/AIDS biologic outcomes, advanced research methodology, biostatistics and epidemiology, and the ethical conduct of research;and participate in related local seminars and national scientific meetings. Scientific Background: The Hispanic community is the largest and fastest growing racial/ethnic minority group in the U.S., and is disproportionately affected by the HIV/AIDS epidemic and myriad social risk factors. However, little is known regarding how sociocultural factors impact antiretroviral adherence in this group. The proposed study will examine the sociocultural determinants of antiretroviral adherence in a sample of HIV+ Hispanic and non-Hispanic white adults using electronic medication monitoring technology. Specific Research Aims: 1) To determine whether sociocultural factors are individually associated with antiretroviral adherence and biological outcomes among HIV+ Hispanics;2) To evaluate the impact of culture on antiretroviral adherence and biological outcomes, after accounting for the impact of social risk factors;and 3) To examine whether sociocultural """"""""risk factors"""""""" mediate the effect of ethnicity on antiretroviral adherence, and to examine explicitly the effects of neuropsychological (NP) functioning in this association. Research Methods: Dr. Rivera Mindt will lead a study of antiretroviral adherence utilizing advanced, electronic medication monitoring technology for 100 HIV+ Hispanic and 50 non-Hispanic white adults. Significance: This study will enhance our understanding of antiretroviral adherence among HIV+ Hispanics &lead to innovative, culturally tailored interventions to increase antiretroviral adherence in this group. This project will also lead to a larger-scale, longitudinal study of sociocultural factors in antiretroviral adherence among this historically under-served group.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Mentored Patient-Oriented Research Career Development Award (K23)
Project #
Application #
Study Section
Behavioral and Social Consequences of HIV/AIDS Study Section (BSCH)
Program Officer
Stoff, David M
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Fordham University
Other Domestic Higher Education
United States
Zip Code
Miranda, Caitlin; Arce RenterĂ­a, Miguel; Fuentes, Armando et al. (2016) [Formula: see text]The Relative Utility of Three English Language Dominance Measures in Predicting the Neuropsychological Performance of HIV+ Bilingual Latino/a Adults. Clin Neuropsychol 30:185-200
Arentoft, Alyssa; Byrd, Desiree; Monzones, Jennifer et al. (2015) Socioeconomic Status and Neuropsychological Functioning: Associations in an Ethnically Diverse HIV+ Cohort. Clin Neuropsychol 29:232-54
Coulehan, Kelly; Byrd, Desiree; Arentoft, Alyssa et al. (2014) The role of decision-making ability in HIV/AIDS: impact on prospective memory. J Clin Exp Neuropsychol 36:730-41
Mindt, Monica Rivera; Miranda, Caitlin; Arentoft, Alyssa et al. (2014) Aging and HIV/AIDS: neurocognitive implications for older HIV-positive Latina/o adults. Behav Med 40:116-23
Gooding, Amanda L; Saperstein, Alice; Rivera Mindt, Monica et al. (2012) Predictors of treatment utilisation at cognitive remediation groups for schizophrenia: the roles of neuropsychological, psychological and clinical variables. Neuropsychol Rehabil 22:516-31
Robbins, Reuben N; D'Aquila, Erica; Morgello, Susan et al. (2012) Cultural influences on antiretroviral therapy adherence among HIV-infected Puerto Ricans. J Assoc Nurses AIDS Care 23:531-8
Arentoft, Alyssa; Byrd, Desiree; Robbins, Reuben N et al. (2012) Multidimensional effects of acculturation on English-language neuropsychological test performance among HIV+ Caribbean Latinas/os. J Clin Exp Neuropsychol 34:814-25
Rivera Mindt, Monica; Byrd, Desiree; Saez, Pedro et al. (2010) Increasing culturally competent neuropsychological services for ethnic minority populations: a call to action. Clin Neuropsychol 24:429-53
Heaton, R K; Clifford, D B; Franklin Jr, D R et al. (2010) HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology 75:2087-96
Robinson-Papp, Jessica; Gonzalez-Duarte, Alejandra; Simpson, David M et al. (2009) The roles of ethnicity and antiretrovirals in HIV-associated polyneuropathy: a pilot study. J Acquir Immune Defic Syndr 51:569-73

Showing the most recent 10 out of 12 publications