The overall goal of this project is to enhance and expand Dr. Christopher Martin's patient-oriented research (POR) program in adolescent and young adult alcohol and drug problems, in the context of mentoring efforts with a set of outstanding trainees who have the potential to be future leaders in the field. Dr. Martin is a mid-career investigator with a strong track record and ongoing funding in POR, and a history of successful mentoring and research training. Effort and salary support will involve intensive mentoring with outstanding young investigators, and career development activities in health disparities and the genetics of addiction that will enhance the mentoring activities. The mentoring and career development activities are highly integrated, with the mutually reinforcing goals of advancing trainee careers and enhancing Dr. Martin's program of POR. Two trainees are junior faculty members with K- awards on which Dr. Martin serves as co-mentor: an NCI grant on the correlates of Nicotine Dependence in African-American youth, and an NIDA grant on substance use and risky sex. Another trainee will begin a postdoctoral fellowship with Dr. Martin as primary mentor beginning 9/2012. Dr. Martin also will mentor three outstanding trainees who will soon finish or have recently finished graduate school. These trainees share Dr. Martin's interests in longitudinal latent variable modeling and/or candidate gene approaches to substance problem phenotypes in the context of developmental and environmental influences. These trainees will collaborate on these topics with Dr. Martin, and he will serve as a mentor helping them develop their next grant proposal as they move on to postdoctoral or junior faculty positions in Pittsburgh or elsewhere. Dr. Martin will identify and mentor other TBN postdoctoral and junior faculty trainees (e.g., those with K23 and K01 support) during the K24 period. There are a rich set of institutional resources available to support the mentoring and research plans.

Public Health Relevance

The overall goal of this project is to enhance and expand Dr. Christopher Martin's patient- oriented research (POR) program in adolescent and young adult alcohol and drug problems, in the context of mentoring efforts with pre-and post-doctoral fellows and junior faculty. The mentoring will help train outstanding young investigators. The research will directly advance knowledge of the causes and clinical course of adolescent and young adult substance problems.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
4K24AA020840-05
Application #
9088190
Study Section
Neuroscience Review Subcommittee (AA)
Program Officer
Scott, Marcia S
Project Start
2012-07-01
Project End
2017-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
5
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Psychiatry
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Chung, Tammy; Creswell, Kasey G; Bachrach, Rachel et al. (2018) Adolescent Binge Drinking. Alcohol Res 39:5-15
Martin, Christopher S; Vergés, Alvaro; Langenbucher, James W et al. (2018) Algorithm Analysis of the DSM-5 Alcohol Withdrawal Symptom. Alcohol Clin Exp Res 42:1073-1083
Chung, Tammy; Cornelius, Jack; Clark, Duncan et al. (2017) Greater Prevalence of Proposed ICD-11 Alcohol and Cannabis Dependence Compared to ICD-10, DSM-IV, and DSM-5 in Treated Adolescents. Alcohol Clin Exp Res 41:1584-1592
Clark, Duncan B; Martin, Christopher S; Chung, Tammy et al. (2016) Screening for Underage Drinking and Diagnostic and Statistical Manual of Mental Disorders, 5th Edition Alcohol Use Disorder in Rural Primary Care Practice. J Pediatr 173:214-20
Creswell, Kasey G; Chung, Tammy; Wright, Aidan G C et al. (2015) Personality, negative affect coping, and drinking alone: a structural equation modeling approach to examine correlates of adolescent solitary drinking. Addiction 110:775-83
Creswell, Kasey G; Chung, Tammy; Clark, Duncan B et al. (2015) Solitary cannabis use in adolescence as a correlate and predictor of cannabis problems. Drug Alcohol Depend 156:120-125
Black, Jessica J; Clark, Duncan B; Martin, Christopher S et al. (2015) Course of alcohol symptoms and social anxiety disorder from adolescence to young adulthood. Alcohol Clin Exp Res 39:1008-15
Martin, Christopher S; Langenbucher, James W; Chung, Tammy et al. (2014) Response to commentaries. Addiction 109:1784-5
Hasler, Brant P; Martin, Christopher S; Wood, D Scott et al. (2014) A longitudinal study of insomnia and other sleep complaints in adolescents with and without alcohol use disorders. Alcohol Clin Exp Res 38:2225-33
Creswell, Kasey G; Chung, Tammy; Clark, Duncan B et al. (2014) Solitary Alcohol Use in Teens Is Associated With Drinking in Response to Negative Affect and Predicts Alcohol Problems in Young Adulthood. Clin Psychol Sci 2:602-610

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