This K24 award is requested by David O. Meltzer, MD, PhD. He is an MD with a PhD in Economics and is currently an Associate Professor at the University of Chicago. His primary appointment is in the Department of Medicine, but he holds secondary appointments in the Irving B. Harris Graduate School of Public Policy Studies and the Department of Economics. Since joining the faculty at the University of Chicago 11 years ago, he has played a major role in the establishment of several major research programs that have come to encompass the work of multiple faculty members, several major training programs that have come to serve as the University's core training resources in health services and outcomes research, and established a major university-wide center for interdisciplinary research in health and the social sciences, the Center for Health and the Social Sciences (CHeSS). His research has focused on the theoretical foundations of medical cost-effectiveness analysis, and on improving the cost and quality of care for hospitalized patients, with a major focus in both areas on addressing issues of greatest relevance to older persons. His work in cost-effectiveness analysis has resulted in the creation of an active and productive group of faculty working collaboratively in the area of medical decision making. His work in hospital medicine has resulted in the development of an Academic Hospitalist Program as a vehicle through which to use our inpatient general medicine services a laboratory for applied social science research in health care quality, making the University of Chicago among the leading programs in hospital medicine nationally. He has been the primary mentor of 33 trainees including PhD students, medical fellows, and junior faculty. This award would support Dr. Meltzer's research, training, and faculty development activities related to cost-effectiveness analysis and hospital care of the elderly.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
Application #
Study Section
National Institute on Aging Initial Review Group (NIA)
Program Officer
Baker, Colin S
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Chicago
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Press, Valerie G; Arora, Vineet M; Trela, Kristin C et al. (2016) Effectiveness of Interventions to Teach Metered-Dose and Diskus Inhaler Techniques. A Randomized Trial. Ann Am Thorac Soc 13:816-24
Wray, Charlie M; Flores, Andrea; Padula, William V et al. (2016) Measuring patient experiences on hospitalist and teaching services: Patient responses to a 30-day postdischarge questionnaire. J Hosp Med 11:99-104
Zhang, James X; Meltzer, David O (2015) Risk factors for cost-related medication non-adherence among older patients with cancer. Integr Cancer Sci Ther 2:300-304
Beveridge, Claire; Knutson, Kristen; Spampinato, Lisa et al. (2015) Daytime Physical Activity and Sleep in Hospitalized Older Adults: Association with Demographic Characteristics and Disease Severity. J Am Geriatr Soc 63:1391-400
Press, Valerie G; Matthiesen, Madeleine I; Ranadive, Alisha et al. (2015) Insights into inpatients with poor vision: A high value proposition. J Hosp Med 10:311-3
Hougham, Gavin W; Ham, Sandra A; Ruhnke, Gregory W et al. (2014) Sequence patterns in the resolution of clinical instabilities in community-acquired pneumonia and association with outcomes. J Gen Intern Med 29:563-71
Shear, Talia C; Balachandran, Jay S; Mokhlesi, Babak et al. (2014) Risk of sleep apnea in hospitalized older patients. J Clin Sleep Med 10:1061-6
Meltzer, David O; Ruhnke, Gregory W (2014) Redesigning care for patients at increased hospitalization risk: the Comprehensive Care Physician model. Health Aff (Millwood) 33:770-7
Stoler, Avraham; Meltzer, David (2013) Mortality and morbidity risks and economic behavior. Health Econ 22:132-43
van Baal, Pieter; Meltzer, David; Brouwer, Werner (2013) Pharmacoeconomic guidelines should prescribe inclusion of indirect medical costs! A response to Grima et Al. Pharmacoeconomics 31:369-73; discussion 375-6

Showing the most recent 10 out of 37 publications