This proposal is for a five year K24 Mid-Career Development Award for patient-oriented research and mentoring for Anthony Harris MD, MPH. The proposal involves research and mentoring in the areas of antimicrobial resistance and hospital epidemiology. At present, he is the principal investigator on one NIH R01 and one CDC R01. During his eight years as a faculty member, he has published more than 70 manuscripts. He has mentored a number of PhD epidemiology students and infectious disease fellows to successful academic careers and has received a mentoring award from the Society of Healthcare Epidemiology of America. He is internationally recognized for his work in the areas of antimicrobial resistance and hospital epidemiology. Dr. Harris is requesting this award to dedicate 50% of his time to mentoring, writing new grants in the areas of infection control interventions aimed at decreasing the emergence of antimicrobial resistance and nosocomial infections, and taking coursework in clinical trials and randomized-cluster design that will improve his patient-oriented research. This award will allow him to decrease his administrative and clinical responsibilities to allow more protected time for mentoring and research. This award will help him achieve his long-term goals, which include: 1) decreasing the incidence of nosocomial infections and decrease the emergence of antimicrobial resistance 2) continuing to successfully obtain NIH R01 funding in the areas of antimicrobial resistance and hospital epidemiology 3) continuing to move his patient-oriented research towards intervention trials including randomized-cluster intervention trials 4) continuing to develop his mentoring skills to mentor trainees to successfully pursue academic clinical research careers.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Midcareer Investigator Award in Patient-Oriented Research (K24)
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Microbiology and Infectious Diseases B Subcommittee (MID)
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Korpela, Jukka K
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University of Maryland Baltimore
Public Health & Prev Medicine
Schools of Medicine
United States
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Jackson, Sarah S; Leekha, Surbhi; Magder, Laurence S et al. (2017) The Effect of Adding Comorbidities to Current Centers for Disease Control and Prevention Central-Line-Associated Bloodstream Infection Risk-Adjustment Methodology. Infect Control Hosp Epidemiol 38:1019-1024
O'Hara, Lyndsay M; Masnick, Max; Leekha, Surbhi et al. (2017) Indirect Versus Direct Standardization Methods for Reporting Healthcare-Associated Infections: An Analysis of Central Line-Associated Bloodstream Infections in Maryland. Infect Control Hosp Epidemiol 38:989-992
Johnson, J Kristie; Robinson, Gwen L; Pineles, Lisa L et al. (2017) Carbapenem MICs in Escherichia coli and Klebsiella Species Producing Extended-Spectrum ?-Lactamases in Critical Care Patients from 2001 to 2009. Antimicrob Agents Chemother 61:
Jackson, Sarah S; Leekha, Surbhi; Magder, Laurence S et al. (2017) Electronically Available Comorbidities Should Be Used in Surgical Site Infection Risk Adjustment. Clin Infect Dis 65:803-810
Pettigrew, Melinda M; Johnson, J Kristie; Harris, Anthony D (2016) The human microbiota: novel targets for hospital-acquired infections and antibiotic resistance. Ann Epidemiol 26:342-7
Masnick, Max; Morgan, Daniel J; Sorkin, John D et al. (2016) Lack of Patient Understanding of Hospital-Acquired Infection Data Published on the Centers for Medicare and Medicaid Services Hospital Compare Website. Infect Control Hosp Epidemiol 37:182-7
Goodman, Katherine E; Lessler, Justin; Cosgrove, Sara E et al. (2016) A Clinical Decision Tree to Predict Whether a Bacteremic Patient Is Infected With an Extended-Spectrum ?-Lactamase-Producing Organism. Clin Infect Dis 63:896-903
Rock, Clare; Thom, Kerri A; Harris, Anthony D et al. (2016) A Multicenter Longitudinal Study of Hospital-Onset Bacteremia: Time for a New Quality Outcome Measure? Infect Control Hosp Epidemiol 37:143-8
Wallace, Lalena; Daugherty, Sean C; Nagaraj, Sushma et al. (2016) Use of Comparative Genomics To Characterize the Diversity of Acinetobacter baumannii Surveillance Isolates in a Health Care Institution. Antimicrob Agents Chemother 60:5933-41
Harris, Anthony D; Jackson, Sarah S; Robinson, Gwen et al. (2016) Pseudomonas aeruginosa Colonization in the Intensive Care Unit: Prevalence, Risk Factors, and Clinical Outcomes. Infect Control Hosp Epidemiol 37:544-8

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