The goal of the current proposal is to provide mentorship for fellows, medical students and undergraduates for careers in global health through participation in patient-oriented research. The research will be conducted with firmly established collaborators at international sites of research excellence in Ghana and Haiti. The projects will stem from research funded by an NIH R01 and two Bill and Melinda Gates Grand Challenge Exploration Awards. These projects will provide experiences in highly innovative clinical translational research in transition from the bench to the bedside. The specific projects are: (1) Endothelial progenitor cells and the pathogenesis of cerebral malaria (2) Re-wiring enteric signaling for preventing cholera (3) A noninvasive cell phone imaging probe for diagnosing malaria. The collaborative research teams for these projects involve scientists from disparate fields such as stem cell biology and engineering working in concert with physician-scientists. The individuals are united in common goals of understanding basic mechanisms of malaria pathogenesis or the development of novel diagnostics and prophylactics for malaria and cholera, respectively. The experiences of trainees participating in these projects will prime them for futures in multidisciplinary collaborative global health research. Combined with complementary didactic studies they will be well prepared to make major advances in this field. In addition, the proposal will provide vital funding to permit me to continue to teach and train those in the global health "pipeline" for these types of careers.

Public Health Relevance

The K24 proposal will support Dr. Linnie Golightly in preparing undergraduates, medical students and physicians for careers in global health. This will be accomplished through mentored research projects of malaria and cholera in Ghana and Haiti.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
1K24AI110732-01
Application #
8679737
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Rao, Malla R
Project Start
2014-08-15
Project End
2019-07-31
Budget Start
2014-08-15
Budget End
2015-07-31
Support Year
1
Fiscal Year
2014
Total Cost
$172,094
Indirect Cost
$12,748
Name
Weill Medical College of Cornell University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065