The goals of the proposed projects are to support my continued development and impact as a mentor, to establish a research training program for patient oriented research (POR) in the Section of Rheumatology at my institution, and to expand my current POR program. Regarding the former, I am strongly committed to devoting a significant percent of my career to mentoring. Among the trainees I am currently working with, I am the primary mentor for 2 junior faculty (1 who is a K awardee), 2 rheumatology fellows interested in pursing a career in POR, and 3 residents planning a career in rheumatology. While my primary interest is in the field of decision making, my training and previous practical experience in epidemiology allow me to be an effective mentor for trainees interested in other aspects of POR related to rheumatic disease. Given my commitment to mentoring, Yale's rich resources dedicated to POR, and strong institutional support to create this program, the K24 Award provides an invaluable opportunity to expand my mentoring efforts and to establish a specialized structured POR curriculum. The program will ensure that fellows interested in becoming independent investigators will be supported by an interdisciplinary team of mentors and will acquire training in clinical research methods and biostatistics. In addition, I will establish a biweekly Research in Progress meeting during which trainees and faculty will be expected to present materials at all stages of development and offer constructive critiques during each session. The training program will include formal mentoring sessions which will adhere to a process for moving research forward. The POR training program will also include formal evaluation of trainees and mentors. In addition to mentoring young investigators, one of my important long-term goals is to advance my own research agenda so that I can continue to conduct scientifically rigorous and meaningful POR. I have established a defined area of expertise and a strong network of collaborators with complementary proficiencies that will support and enhance my research program. Current examples include collaborations with Dr. Curtis (UAB) with whom I have recently submitted a grant to develop individualized outcome estimates in rheumatoid arthritis, Drs. Reyna (Cornell) and Peters (Ohio State) who are basic science experts in decision making and are current collaborators on a project to develop a decision aid in rheumatoid arthritis, Dr. Almazor (MD Anderson) with whom I am working on 2 projects examining the value of conjoint analysis in patients with knee OA, and Dr. Street (Baylor College of Medicine) an internationally renowned expert on communication, who is a collaborator on a new research project: Measuring Patients'Risk Perceptions in Real Time. New planned studies will continue to focus on understanding the reasons underlying poor quality decision making in clinical practice and I will expand my current projects to include randomized controlled trials to test the efficacy/effectiveness of the tools developed.

Public Health Relevance

The goals of the proposed project are to support my continued development and impact as a mentor, to establish a research training program for patient oriented research in rheumatology at my institution, and to expand my current research program. I have found that mentoring persons from various backgrounds who share a passion to design high quality studies in order to improve the methods by which we deliver health care to be the most rewarding aspect of my job. The K24 Award would ensure that I have the protected time to be able to expand my current mentoring activities while continuing to advance my own patient oriented research program to improve medical decision making in patients with rheumatic disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24AR060231-04
Application #
8698168
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Witter, James
Project Start
2011-07-01
Project End
2016-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
New Haven
State
CT
Country
United States
Zip Code
06510
Dorflinger, Lindsey M; Kulkarni, Sanjay; Thiessen, Carrie et al. (2017) Assessing Living Donor Priorities Through Nominal Group Technique. Prog Transplant :1526924817746682
Jiang, Charles Changchuan; Fraenkel, Liana (2017) The Influence of Varying Cost Formats on Preferences. Med Decis Making 37:17-26
Makris, Una E; Weinreich, Mark A; Fraenkel, Liana et al. (2017) Restricting Back Pain and Subsequent Disability in Activities of Daily Living Among Community-Living Older Adults. J Aging Health :898264317721555
Wang, Shi-Yi; Kelly, Gabrielle; Gross, Cary et al. (2017) Information Needs of Older Women With Early-Stage Breast Cancer When Making Radiation Therapy Decisions. Int J Radiat Oncol Biol Phys 98:733-740
Toupin-April, Karine; Barton, Jennifer; Fraenkel, Liana et al. (2017) Toward the Development of a Core Set of Outcome Domains to Assess Shared Decision-making Interventions in Rheumatology: Results from an OMERACT Delphi Survey and Consensus Meeting. J Rheumatol 44:1544-1550
Solomon, Daniel H; Losina, Elena; Lu, Bing et al. (2017) Implementation of Treat-to-Target in Rheumatoid Arthritis Through a Learning Collaborative: Results of a Randomized Controlled Trial. Arthritis Rheumatol 69:1374-1380
McDougall, John A; Ferucci, Elizabeth D; Glover, Janis et al. (2017) Telerheumatology: A Systematic Review. Arthritis Care Res (Hoboken) 69:1546-1557
Fraenkel, Liana; Stolar, Marilyn; Swift, Sarah et al. (2017) Subjective Numeracy and the Influence of Order and Amount of Audible Information on Perceived Medication Value. Med Decis Making 37:230-238
Eyler, Rachel F; Cordes, Sara; Szymanski, Benjamin R et al. (2017) Utilization of Continuous ""Spinners"" to Communicate Risk. Med Decis Making 37:725-729
Hsiao, Betty; Fraenkel, Liana (2017) Incorporating the patient's perspective in outcomes research. Curr Opin Rheumatol 29:144-149

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