The K24 Midcareer Investigator Award presents Dr. Chenchen Wang with an exciting opportunity to collaborate with renowned scientists at Tufts, Brown, Harvard, and Boston University Schools of Medicine to mentor new investigators who wish to contribute to patient-oriented research in Complementary and Alternative Medicine (CAM). Currently Dr. Wang is Associate Professor at Tufts University School of Medicine and Director of the Tufts Center for Complementary and Integrative Medicine, with a strong record of research, publication, and mentoring. She is the Principal Investigator of two NIH-funded R01 projects studying comparative-effectiveness and cost-effectiveness of mind-body interventions for osteoarthritis and fibromyalgia, as well as post-traumatic stress disorder in military populations Dr. Wang's long-term goal is to advance the science of mind-body medicine to promote health and healing. Her immediate goals are to obtain protected time to train the next generation of CAM scientists in patient- oriented research and to expand her innovative, multi-method, multidisciplinary clinical and translational research programs for chronic disabling conditions. Dr. Wang has an established track record of effectively mentoring trainees at various levels with diverse backgrounds, including clinicians from different countries and disciplines. Her CAM mentoring program, as well as her expertise on mind-body interventions, has been fully integrated into the research and teaching infrastructure of the Tufts Clinical and Translational Science Institute. Combined with outstanding resources and a long-recognized diverse training environment, these selected mentees will obtain training in rigorous scientific methodology, integrity, ethics, and grant applications necessary to stimulate high-quality, translational, patient-oriented research with a multidisciplinary team. Building upon NCCAM-funded R21 and R01 studies, the proposed research aims to:1) Evaluate comparative effectiveness and cost-effectiveness of mind-body interventions;2) Elucidate neurobiological mechanisms of CAM therapies;3) Investigate unmet needs of novel and cost-effective CAM treatments;4) Create comprehensive interdisciplinary approaches in CAM training;5) Develop the scientific and structural foundations for future R01 and other program applications;6) Extend opportunities to new scientists to integrate CAM into mainstream institutions and research settings. This K24 will therefore promote multidisciplinary patient-oriented research for the next generation of investigators in order to substantially advance the science on integrative medicine and the contributions to health, health care, and well-being for all.

Public Health Relevance

Complementary and integrative medicine approaches offer the potential to positively affect the progression of disease, while simultaneously diminishing pain and morbidity. This Midcareer Investigator Award will support the implementation of a multidisciplinary mentoring and research program for the next generation of CAM researchers. The program will substantially advance the science of mind-body medicine to contribute to cost- effective healthcare and the direction of future medicine.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
1K24AT007323-01A1
Application #
8635655
Study Section
Special Emphasis Panel (ZAT1-PK (26))
Program Officer
Khalsa, Partap Singh
Project Start
2013-12-01
Project End
2018-11-30
Budget Start
2013-12-01
Budget End
2014-11-30
Support Year
1
Fiscal Year
2014
Total Cost
$168,456
Indirect Cost
$12,478
Name
Tufts University
Department
Type
DUNS #
079532263
City
Boston
State
MA
Country
United States
Zip Code
02111
Niles, Barbara L; Mori, DeAnna L; Polizzi, Craig P et al. (2016) Feasibility, qualitative findings and satisfaction of a brief Tai Chi mind-body programme for veterans with post-traumatic stress symptoms. BMJ Open 6:e012464
Lee, A C; Harvey, W F; Price, L L et al. (2016) Mindfulness is associated with psychological health and moderates pain in knee osteoarthritis. Osteoarthritis Cartilage :
Marszalek, Jolanta; Price, Lori Lyn; Harvey, William F et al. (2016) Outcome Expectations and Osteoarthritis: Perceived Benefits of Exercise Are Associated with Self-Efficacy and Depression. Arthritis Care Res (Hoboken) :
Iversen, Maura D; Price, Lori Lyn; von Heideken, Johan et al. (2016) Physical examination findings and their relationship with performance-based function in adults with knee osteoarthritis. BMC Musculoskelet Disord 17:273
Reid, Kieran F; Fielding, Roger A; Price, Lori Lyn et al. (2016) Reply. Arthritis Rheumatol 68:1047-8
Wang, Chenchen; Schmid, Christopher H; Iversen, Maura D et al. (2016) Comparative Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis: A Randomized Trial. Ann Intern Med 165:77-86
Reid, Kieran F; Price, Lori Lyn; Harvey, William F et al. (2015) Muscle Power Is an Independent Determinant of Pain and Quality of Life in Knee Osteoarthritis. Arthritis Rheumatol 67:3166-73
Driban, Jeffrey B; Morgan, Nani; Price, Lori Lyn et al. (2015) Patient-Reported Outcomes Measurement Information System (PROMIS) instruments among individuals with symptomatic knee osteoarthritis: a cross-sectional study of floor/ceiling effects and construct validity. BMC Musculoskelet Disord 16:253
Wang, Chenchen; McAlindon, Timothy; Fielding, Roger A et al. (2015) A novel comparative effectiveness study of Tai Chi versus aerobic exercise for fibromyalgia: study protocol for a randomized controlled trial. Trials 16:34
Wang, Chenchen; Iversen, Maura D; McAlindon, Timothy et al. (2014) Assessing the comparative effectiveness of Tai Chi versus physical therapy for knee osteoarthritis: design and rationale for a randomized trial. BMC Complement Altern Med 14:333

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