This K24 renewal application for a Mid-Career Investigator Award in Patient-Oriented Research will continue to provide me with the protected time necessary to focus my research and mentoring at the leading edge of substance abuse and infectious diseases. During the past 4 years of the current K24,1have been the PI on seven federally-funded (NIDA, SAMHSA, HRSA, CDC) awards, totaling more than $12 million. During this same time, I have co-authored 40 peer-reviewed scientific papers, six chapters in books and have been invited to present at numerous national and international meetings. I have successfully mentored many junior investigators with whom I co-author manuscripts;three have received K23 awards, one has an R21 and an R01, two have R21s under review and others received smaller grants through foundations, the pharmaceutical industry and professional organizations. Through this K24, my goals are to continue: 1) my productivity in patient-oriented research;2) mentorship of junior investigators;and 3) to increase the awareness of the interface between substance abuse and infectious diseases. As part of this K24 application, I also intend to extend my work globally. My research to date has broadly involved epidemiological, health services outcomes and intervention studies involving drug users with or at risk for HIV. My focus has involved interventions targeting out-of-treatment drug users - primarily in community, HIV clinical care, drug treatment and correctional settings. These settings are complementary as HIV+ drug users (HIDUs) filter between these areas and each offers unique opportunities for intervention. Specifically, I am now developing NIDA-funded programs of directly administered antiretroviral therapy (DAART) in community and correctional settings and as part of prison- and jail-release programs. I am also investigating secondary HIV prevention strategies for HIDUs in these settings. I am fortunate to now be collaborating with colleagues in Eastern Europe and Southeast Asia. We are currently in the midst of developing novel treatment intervention and HIV risk-reduction research in these settings. This preliminary work will provide unique opportunities to expand evidence-based interventions and treatment globally to settings profoundly affected by drug use and infectious diseases. If allowed to continue on my current trajectory, I am likely to be able to achieve my short- and long-term career development goals.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Midcareer Investigator Award in Patient-Oriented Research (K24)
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Application #
Study Section
Special Emphasis Panel (ZDA1-KXH-C (19))
Program Officer
Jones, Dionne
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Fiscal Year
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Yale University
Internal Medicine/Medicine
Schools of Medicine
New Haven
United States
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Boyd, Andrew T; Song, Dahye L; Meyer, Jaimie P et al. (2015) Emergency department use among HIV-infected released jail detainees. J Urban Health 92:108-35
Krishnan, Archana; Ferro, Enrico G; Weikum, Damian et al. (2015) Communication technology use and mHealth acceptance among HIV-infected men who have sex with men in Peru: implications for HIV prevention and treatment. AIDS Care 27:273-82
Bazazi, Alexander R; Zelenev, Alexei; Fu, Jeannia J et al. (2015) High prevalence of non-fatal overdose among people who inject drugs in Malaysia: Correlates of overdose and implications for overdose prevention from a cross-sectional study. Int J Drug Policy 26:675-81
Carver, Jasmine W; Dévieux, Jessy G; Gaston, Stéphanie C et al. (2014) Sexual risk behaviors among adolescents in Port-au-Prince, Haiti. AIDS Behav 18:1595-603
Izenberg, Jacob M; Bachireddy, Chethan; Wickersham, Jeffrey A et al. (2014) Within-prison drug injection among HIV-infected Ukrainian prisoners: prevalence and correlates of an extremely high-risk behaviour. Int J Drug Policy 25:845-52
Brown, Shan-Estelle; Altice, Frederick L (2014) Self-management of buprenorphine/naloxone among online discussion board users. Subst Use Misuse 49:1017-24
Vagenas, Panagiotis; Ludford, Kaysia T; Gonzales, Pedro et al. (2014) Being unaware of being HIV-infected is associated with alcohol use disorders and high-risk sexual behaviors among men who have sex with men in Peru. AIDS Behav 18:120-7
Jin, Harry; Earnshaw, Valerie A; Wickersham, Jeffrey A et al. (2014) An assessment of health-care students' attitudes toward patients with or at high risk for HIV: implications for education and cultural competency. AIDS Care 26:1223-8
Meyer, Jaimie P; Cepeda, Javier; Springer, Sandra A et al. (2014) HIV in people reincarcerated in Connecticut prisons and jails: an observational cohort study. Lancet HIV 1:e77-e84
Meyer, Jaimie P; Cepeda, Javier; Wu, Johnny et al. (2014) Optimization of human immunodeficiency virus treatment during incarceration: viral suppression at the prison gate. JAMA Intern Med 174:721-9

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