The major objectives of the proposed Pathway to Independence Award are the acceleration and completion of Dr. Matthew Lee's training in developmental alcohol research and the launching of his career as an independent scientist. Dr. Lee is a postdoctoral fellow nearing completion of an NIAAA-funded T32 training fellowship in the department of Psychological Sciences at the University of Missouri (MU). The two-year training (K99) phase of the proposed project will complete Dr. Lee's training in the examination of processes of pathological drinking desistance across the lifespan. With supervision, Dr. Lee will conduct research assessing how the processes that drive desistance from pathological drinking may vary across developmental stages. He will receive training via coursework, readings, and consultation to increase his knowledge of integrative data analysis, data collection methodology, strategies for conducting practically-informative research, developmental issues of midlife and older adults, theories of desistance from pathological drinking, and multilevel structural equation modeling. He will attend conferences related to alcohol use/misuse and developmental issues of young adulthood and older adulthood. Dr. Lee will also dedicate a great deal of his time to the dissemination of findings from the proposed research through manuscript preparation and submission. The proposed mentor (Dr. Sher) and collaborators/consultants (Drs. Curran, Hussong, Bauer, Heath, Bucholz, Chassin, Dearing, Caspi, Infurna, and Steinley) collectively provide expertise that is ideally suited to facilitate te successful completion of the proposed training and research activities. Further, MU is a world-class research institution, with the resources necessary to facilitate successful completion of the training (K99) phase of this proposed project. The three-year independent (R00) phase will allow Dr. Lee to further examine processes of pathological drinking desistance among midlife and older adults via new data collection. This work will greatly extend Dr. Lee's past research on young adult developmental changes in risky drinking, including in ways that address NIAAA's emphases on lifespan development and the need for greater empirical attention to risky drinking among midlife and older adults.

Public Health Relevance

Briefly, the proposed research is aimed at helping researchers and clinicians better understand how the processes that drive desistance from risky drinking may vary across individuals of different developmental stages. This work has the potential to advance the field toward a more unified understanding of risky drinking across the lifespan, thus addressing NIAAA's emphases on lifespan development and the need for greater empirical attention to risky drinking in midlife and older adults. Further, greater knowledge of developmental variability in desistance processes could be leveraged toward tailoring clinical and public health intervention efforts for individuals of different developmental stages.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Career Transition Award (K99)
Project #
1K99AA024236-01A1
Application #
9109809
Study Section
Neuroscience Review Subcommittee (AA)
Program Officer
Shirley, Mariela
Project Start
2016-05-01
Project End
2018-04-30
Budget Start
2016-05-01
Budget End
2017-04-30
Support Year
1
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Missouri-Columbia
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
153890272
City
Columbia
State
MO
Country
United States
Zip Code
65211
Lee, Matthew R; Sher, Kenneth J (2018) ""Maturing Out"" of Binge and Problem Drinking. Alcohol Res 39:31-42
Lee, Matthew R; Boness, Cassandra L; McDowell, Yoanna E et al. (2018) Desistance and Severity of Alcohol Use Disorder: A Lifespan-Developmental Investigation. Clin Psychol Sci 6:90-105