The Yale Center for Clinical Investigation (YCCI) was created to provide a """"""""home"""""""" for training the next? generation of clinical investigators. Key programmatic goals are to 1) attract highly talented students and? junior faculty across medicine, nursing, public health, biological sciences and biomedical engineering; and? train them in the use of state-of-the-art research tools; give them the skills to work within complex research? teams; and support their professional development; and 2) foster the translation of disease-related? discoveries from the laboratory into the community by: stimulating the creation of interdisciplinary teams;? making available state-of-the-art core facilities and expanded biostatistical and bioinformatics resources;? establishing organizational and regulatory infrastructure for clinical studies; and forging a dynamic new? partnership that will integrate community leaders, physicians, and health centers. Participating institutions? include the Schools of Medicine, Nursing, Public Health, the Department of Biomedical Engineering and? Graduate Programs in Biological and Biomedical Sciences. The Investigative Medicine program (IMP) is? central to YCCI's education and training efforts. It is a unique doctoral program that offers Ph.D. degrees in? Health Sciences Research to highly qualified M.D. fellows embarking on careers in translational or clinical? research. IMP will be expanded with CTSA support to include nursing, public health, biological sciences,? and MD-PhD students. YCCI has also created a Society of YCCI Faculty Mentors who will participate? actively in the training and nurturing of the students and junior faculty members identified as YCCI Clinical? Scholars. Pilot and feasibility (P&F) grants will be awarded for 1) junior faculty; 2) interdisciplinary? translational teams; 3) new technologies; and 4) community-based projects. YCCI will cluster research? cores around common themes.including: imaging; specimen analysis; physiology; cognition and behavior;? drug development; and cell therapy. A new Office of Research Services will provide facilities for """"""""one-stop""""""""? shopping for regulatory, biostatistical, bioinformatics, recruitment and other support services. YCCI will have? an office to coordinate the University's efforts to address health issues facing our community. The? University's decision to immediately provide substantial support to establish the YCCI reflects its strong? commitment to an innovative redesign of our clinical and translational research activities.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Mentored Career Development Award (KL2)
Project #
5KL2RR024138-02
Application #
7294942
Study Section
Special Emphasis Panel (ZRR1-CR-3 (01))
Program Officer
Merchant, Carol
Project Start
2006-09-30
Project End
2011-06-30
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
2
Fiscal Year
2007
Total Cost
$873,504
Indirect Cost
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Dharmarajan, Kumar; Wang, Yongfei; Lin, Zhenqiu et al. (2017) Association of Changing Hospital Readmission Rates With Mortality Rates After Hospital Discharge. JAMA 318:270-278
Petrulli, J Ryan; Hansen, Søren B; Abourbeh, Galith et al. (2017) A multi species evaluation of the radiation dosimetry of [11C]erlotinib, the radiolabeled analog of a clinically utilized tyrosine kinase inhibitor. Nucl Med Biol 47:56-61
Babayev, Elnur; Lalioti, Maria D; Favero, Federico et al. (2016) Cross-Talk Between FSH and Endoplasmic Reticulum Stress: A Mutually Suppressive Relationship. Reprod Sci 23:352-64
Yang, Cai-Rong; Lowther, Katie M; Lalioti, Maria D et al. (2016) Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice. Endocrinology 157:405-16
Mitchell, Hannah-Rose; Lu, Xiaomin; Myers, Regina M et al. (2016) Prospective, longitudinal assessment of quality of life in children from diagnosis to 3 months off treatment for standard risk acute lymphoblastic leukemia: Results of Children's Oncology Group study AALL0331. Int J Cancer 138:332-9
Cyrus, Nika; Mai-Anh Bui, Christine; Yao, Xiaopan et al. (2016) Density and Polarization States of Tumor-Associated Macrophages in Human Cutaneous Squamous Cell Carcinomas Arising in Solid Organ Transplant Recipients. Dermatol Surg 42 Suppl 1:S18-23
Goffredo, Martina; Caprio, Sonia; Feldstein, Ariel E et al. (2016) Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study. Hepatology 63:117-25
Balsamo, Lyn M; Sint, Kyaw J; Neglia, Joseph P et al. (2016) The Association Between Motor Skills and Academic Achievement Among Pediatric Survivors of Acute Lymphoblastic Leukemia. J Pediatr Psychol 41:319-28
Bearss, Karen; Burrell, T Lindsey; Stewart, Lindsay et al. (2015) Parent Training in Autism Spectrum Disorder: What's in a Name? Clin Child Fam Psychol Rev 18:170-82
Womack, Julie A; Brandt, Cynthia A; Justice, Amy C (2015) Primary care of women aging with HIV. J Midwifery Womens Health 60:146-57; quiz 225

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