The Rochester Clinical and Translational Science Award (RCTSA) Program proposes continuation of its dual goals: 1) To organize, support, and expand clinical and translational research at the University of Rochester within an academic home, the University of Rochester Clinical and Translational Science Institute (URCTSI), and 2) To integrate and collaborate with regional and national institutions to expand a National Clinical and Translational Research Network. The RCTSA Program has truly transformed the University of Rochester Medical Center (URMC), with the construction of a state-of-the-art Clinical and Translational Science Building, the integration of clinical and translational science into the shared vision for URMC research, a successful system of dynamic governance, expansion of research resources, and enthusiastic participation and leadership in the National CTSA Consortium. To continue this momentum, the UR-CTSI will carry out a number of specific aims. First, three new key functions will be implemented: Public-Private Partnerships, T1 Translation, and Comparative Effectiveness Research. Existing Key Functions will be reorganized and consolidated to provide better support of investigators by an expanded Office of Regulatory Support, a Navigator/Consultation Service, and an Incubator Program consolidating Pilot Studies, Novel Methodologies, and Translational Technologies Key Functions. The CTSI will establish and foster four centers of research excellence across the spectrum of research translation: Center for Human Experimental Therapeutics (T1 Research);Clinical Research Center (T1-3 Research);Center for Research Implementation and Translation (T2-3 research under School of Nursing sponsorship);and Center for Community Health (T2-3 research). A broad range of education, training, and career development programs will continue to meet research workforce needs. The UR-CTSI will be an active participant in the National CTSA consortium with sharing of expertise, methods, data, and curricula. The Upstate New York Translational Research Network (UNYTRN) will be expanded to support the region's biomedical research institutions. Finally, the UR-CTSI will be evaluated through the measurement of rigorous performance outcomes.
The UR Clinical and Translational Science Institute (UR-CTSI) will be the focal point for translation of basic discoveries to human applications and clinical trials, and for evidence-based implementation of efficacious clinical practices and effective community strategies. The UR CTSI will be a model for CTSA involvement of nursing, dentistry, and other disciplines, for engagement of the Rochester community in all aspects of research.and for collaboration with regional biomedical institutions in research translation.
|Chen, Wei; Abramowitz, Matthew K (2017) Epidemiology of Acid-Base Derangements in CKD. Adv Chronic Kidney Dis 24:280-288|
|Abar, Beau; Hong, Steven; Aaserude, Eric et al. (2017) Access to Care and Depression among Emergency Department Patients. J Emerg Med 53:30-37|
|Lin, Feng; Ren, Ping; Mapstone, Mark et al. (2017) The cingulate cortex of older adults with excellent memory capacity. Cortex 86:83-92|
|Lin, Feng; Heffner, Kathi L; Ren, Ping et al. (2017) A Role of the Parasympathetic Nervous System in Cognitive Training. Curr Alzheimer Res 14:784-789|
|Liu, X; Ma, L; Zhang, S et al. (2017) CD73 Controls Extracellular Adenosine Generation in the Trigeminal Nociceptive Nerves. J Dent Res 96:671-677|
|Shum, Laura C; White, Noelle S; Nadtochiy, Sergiy M et al. (2016) Cyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging Bone. PLoS One 11:e0155709|
|Bao, Yangyang; Willis, B Cicero; Frasier, Chad R et al. (2016) Scn2b Deletion in Mice Results in Ventricular and Atrial Arrhythmias. Circ Arrhythm Electrophysiol 9:|
|Lin, Feng; Heffner, Kathi L; Ren, Ping et al. (2016) Cognitive and Neural Effects of Vision-Based Speed-of-Processing Training in Older Adults with Amnestic Mild Cognitive Impairment: A Pilot Study. J Am Geriatr Soc 64:1293-8|
|Pisani, Anthony R; Murrie, Daniel C; Silverman, Morton M (2016) Reformulating Suicide Risk Formulation: From Prediction to Prevention. Acad Psychiatry 40:623-9|
|Adler, David H; Wallace, Melissa; Bennie, Thola et al. (2016) Cumulative Impact of HIV and Multiple Concurrent Human Papillomavirus Infections on the Risk of Cervical Dysplasia. Adv Virol 2016:7310894|
Showing the most recent 10 out of 132 publications