The Yale Center for Clinical Investigation (YCCI) was created to provide a """"""""home"""""""" for training the next generation of clinical investigators. Key programmatic goals are to 1) attract highly talented students and junior faculty across medicine, nursing, public health, biological sciences and biomedical engineering;and train them in the use of state-of-the-art research tools;give them the skills to work within complex research teams;and support their professional development;and 2) foster the translation of disease-related discoveries from the laboratory into the clinic and then the community by: stimulating the creation of interdisciplinary teams;making available state-of-the-art core facilities and expanded biostatistical and bioinformatics resources;establishing organizational and regulatory infrastructure for clinical studies;and forging new partnerships that will integrate community leaders, physicians, and health centers and encourage participation in research. Participating institutions include the Schools of Medicine, Nursing, and Public Health, the department of Biomedical Engineering and the Graduate Programs in Biological and Biomedical Sciences. The Junior Faculty Scholars award program and the Investigative Medicine program (IMP) are central to YCCI's education and training efforts. IMP is a unique doctoral program that offers Ph.D. degrees in Health Sciences Research to highly qualified M.D. fellows embarking on careers in translational or clinical research and the junior faculty scholars program is a career development program. YCCI has also created a Society of Mentors who participate actively in the training and nurturing of the YCCI Scholars. Pilot and feasibility (P&F) grants will be awarded for: 1) interdisciplinary translational team research;2) development of novel methodologies;3) Use of Core (inci imaging) technologies;and 4) community-based research. YCCI will cluster research cores around common themes, including: imaging;genomics and proteomics;cell and tissue based tech;Integrated metabolics;cognition and biobehavior;and animal models. The Office of Research Services will provide robust facilities and resources for regulatory, biostatistical, bioinformatics, recruitment and other support services. YCCI will have an office to coordinate the University's efforts to address health issues facing our community and our national community.

Public Health Relevance

This research has direct relevance to public health in that its goals are to facilitate clinical research, including by training the next generation of clinical researchers, that will lead to better treatments for human disease and better health outcomes.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Mentored Career Development Award (KL2)
Project #
5KL2TR000140-09
Application #
8743317
Study Section
Special Emphasis Panel (ZRR1-CR-1 (01))
Program Officer
Merchant, Carol
Project Start
2006-09-30
Project End
2016-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
9
Fiscal Year
2014
Total Cost
$678,050
Indirect Cost
$57,366
Name
Yale University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Kong, Grace; Smith, Philip H; Pilver, Corey et al. (2016) Problem-gambling severity and psychiatric disorders among American-Indian/Alaska native adults. J Psychiatr Res 74:55-62
Niccolai, Linda M; Hansen, Caitlin E; Credle, Marisol et al. (2016) Parents' Recall and Reflections on Experiences Related to HPV Vaccination for Their Children. Qual Health Res 26:842-50
Bi, Mark; Zhao, Siming; Said, Jonathan W et al. (2016) Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma. Proc Natl Acad Sci U S A 113:2170-5
Crawford, Forrest W; Stutz, Timothy C; Lange, Kenneth (2016) Coupling bounds for approximating birth-death processes by truncation. Stat Probab Lett 109:30-38
Xie, Zuoquan; Lee, Young H; Boeke, Marta et al. (2016) MET Inhibition in Clear Cell Renal Cell Carcinoma. J Cancer 7:1205-14
Morean, Meghan E; Kong, Grace; Camenga, Deepa R et al. (2016) Latent class analysis of current e-cigarette and other substance use in high school students. Drug Alcohol Depend 161:292-7
Hansen, Caitlin E; Credle, Marisol; Shapiro, Eugene D et al. (2016) ""It All Depends"": A Qualitative Study of Parents' Views of Human Papillomavirus Vaccine for their Adolescents at Ages 11-12 years. J Cancer Educ 31:147-52
Kunkel, Amber; Crawford, Forrest W; Shepherd, James et al. (2016) Benefits of continuous isoniazid preventive therapy may outweigh resistance risks in a declining TB/HIV co-epidemic. AIDS :
Wormser, Gary P; Sudhindra, Praveen; Lopez, Eliana et al. (2016) Fatigue in patients with erythema migrans. Diagn Microbiol Infect Dis 86:322-326
Onyeama, Sara-Jane N; Hanson, Sheila J; Dasgupta, Mahua et al. (2016) Factors Associated With Continuous Low-Dose Heparin Infusion for Central Venous Catheter Patency in Critically Ill Children Worldwide. Pediatr Crit Care Med 17:e352-61

Showing the most recent 10 out of 58 publications