The Yale Center for Clinical Investigation (YCCI) was created to provide a """"""""home"""""""" for training the next generation of clinical investigators. Key programmatic goals are to 1) attract highly talented students and junior faculty across medicine, nursing, public health, biological sciences and biomedical engineering;and train them in the use of state-of-the-art research tools;give them the skills to work within complex research teams;and support their professional development;and 2) foster the translation of disease-related discoveries from the laboratory into the clinic and then the community by: stimulating the creation of interdisciplinary teams;making available state-of-the-art core facilities and expanded biostatistical and bioinformatics resources;establishing organizational and regulatory infrastructure for clinical studies;and forging new partnerships that will integrate community leaders, physicians, and health centers and encourage participation in research. Participating institutions include the Schools of Medicine, Nursing, and Public Health, the department of Biomedical Engineering and the Graduate Programs in Biological and Biomedical Sciences. The Junior Faculty Scholars award program and the Investigative Medicine program (IMP) are central to YCCI's education and training efforts. IMP is a unique doctoral program that offers Ph.D. degrees in Health Sciences Research to highly qualified M.D. fellows embarking on careers in translational or clinical research and the junior faculty scholars program is a career development program. YCCI has also created a Society of Mentors who participate actively in the training and nurturing of the YCCI Scholars. Pilot and feasibility (P&F) grants will be awarded for: 1) interdisciplinary translational team research;2) development of novel methodologies;3) Use of Core (inci imaging) technologies;and 4) community-based research. YCCI will cluster research cores around common themes, including: imaging;genomics and proteomics;cell and tissue based tech;Integrated metabolics;cognition and biobehavior;and animal models. The Office of Research Services will provide robust facilities and resources for regulatory, biostatistical, bioinformatics, recruitment and other support services. YCCI will have an office to coordinate the University's efforts to address health issues facing our community and our national community.
This research has direct relevance to public health in that its goals are to facilitate clinical research, including by training the next generation of clinical researchers, that will lead to better treatments for human disease and better health outcomes.
|Ding, Qinglan; Redeker, Nancy S; Pisani, Margaret A et al. (2017) Factors Influencing Patients' Sleep in the Intensive Care Unit: Perceptions of Patients and Clinical Staff. Am J Crit Care 26:278-286|
|Kluger, Harriet M; Zito, Christopher R; Turcu, Gabriela et al. (2017) PD-L1 Studies Across Tumor Types, Its Differential Expression and Predictive Value in Patients Treated with Immune Checkpoint Inhibitors. Clin Cancer Res 23:4270-4279|
|Kong, Grace; Idrisov, Bulat; Galimov, Artur et al. (2017) Electronic Cigarette Use Among Adolescents in the Russian Federation. Subst Use Misuse 52:332-339|
|Hwang, Janice J; Jiang, Lihong; Hamza, Muhammad et al. (2017) The human brain produces fructose from glucose. JCI Insight 2:e90508|
|Kong, Grace; Unger, Jennifer; Baezconde-Garbanati, Lourdes et al. (2017) The Associations between Yelp Online Reviews and Vape Shops Closing or Remaining Open One Year Later. Tob Prev Cessat 2:|
|Simon, Patricia; Camenga, Deepa R; Kong, Grace et al. (2017) Youth E-cigarette, Blunt, and Other Tobacco Use Profiles: Does SES Matter? Tob Regul Sci 3:115-127|
|Ventola, Pamela; Lei, Jiedi; Paisley, Courtney et al. (2017) Parenting a Child with ASD: Comparison of Parenting Style Between ASD, Anxiety, and Typical Development. J Autism Dev Disord 47:2873-2884|
|Grossman, Matthew R; Berkwitt, Adam K; Osborn, Rachel R et al. (2017) An Initiative to Improve the Quality of Care of Infants With Neonatal Abstinence Syndrome. Pediatrics 139:|
|Altman, Marcus T; Knauert, Melissa P; Pisani, Margaret A (2017) Sleep Disturbance after Hospitalization and Critical Illness: A Systematic Review. Ann Am Thorac Soc 14:1457-1468|
|Culbert, Gabriel J; Crawford, Forrest W; Murni, Astia et al. (2017) Predictors of Mortality within Prison and after Release among Persons Living with HIV in Indonesia. Res Rep Trop Med 8:25-35|
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