Washington University (WU) School of Medicine is linked with BJC Healthcare, one of the largest and most diverse non-profit health systems in the U.S including two """"""""top 10"""""""" teaching hospitals;Barnes Jewish Hospital and St. Louis Children's Hospital. WU is an outstanding environment for research, research training, and clinical care. We are applying for an Institutional Comparative Effectiveness Research (CER) Mentored Career Development Award (KM1) (RFA-OD-10-011) at WU to expand the workforce capable of performing CER. We will use existing infrastructure at WU including the Center for Clinical Research Training, Institute of Public Health and Institute for Clinical and Translational Sciences to develop and implement a new CER Career Development Program. We propose the following Specific Aims: 1. Develop and implement mentored hands-on CER training experiences using research data, administrative data, and electronic health records. Provide CER training opportunities to CER scholars and other investigators from diverse disciplines. 2. Develop and implement new CER curricula, classes, and short term training in the existing Masters of Science in Clinical Investigation (MSCI) degree and the new Masters of Science in Population Health (MSPH) degree at Washington University. 3. Create six new CER scholar positions in the Clinical Research Training Center at Washington University to support postdoctoral fellows and junior and mid career faculty focused on CER. CER scholars will participate in mentored hands-on CER experiences, didactic coursework and training to expand and strengthen the CER workforce 4. Establish a comprehensive system to evaluate the CER Career Development Program. We will evaluate scholars, faculty, mentors and training using real time surveys and input from an external advisory board. The long term impact of this program to strengthen the CER workforce will be measured by tracking abstracts, publications, grants and career development of the CER scholars and others participating in the CER training over the next 10 years. WU has excellent faculty, mentors and infrastructure to support this new CER Career Development Program and an outstanding pool of potential scholars. Establishing this new CER Career Development Program at WU will expand and enhance the pool of investigators qualified to perform CER to identify the best treatments, drugs and procedures to use in real world settings to improve public health and reduce healthcare costs.
This grant provides protected time, salary support, and research training for investigators from diverse disciplines to obtain specialized skills in comparative effectiveness research. These well trained investigators will conduct research to determine the best treatments, tests and procedures for patients in real world settings which will improve health outcomes and reduces costs for unnecessary or ineffective treatments. Comparative effectiveness research will provide important new knowledge to inform patients, providers and payers about which treatments and procedures work best in which patients.
|Si, Sheng; Durkin, Michael J; Mercier, Maureen M et al. (2017) Successful Treatment of Prosthetic Joint Infection due to Vancomycin-resistant Enterococci with Tedizolid. Infect Dis Clin Pract (Baltim Md) 25:105-107|
|Graboyes, Evan M; Kallogjeri, Dorina; Saeed, Mohammed J et al. (2017) 30-day hospital readmission following otolaryngology surgery: Analysis of a state inpatient database. Laryngoscope 127:337-345|
|Cedars, Ari; Benjamin, Lawrence; Burns, Sara V et al. (2017) Clinical predictors of length of stay in adults with congenital heart disease. Heart 103:1258-1263|
|Saeed, Mohammed J; Olsen, Margaret A; Powderly, William G et al. (2017) Diabetes Mellitus is Associated With Higher Risk of Developing Decompensated Cirrhosis in Chronic Hepatitis C Patients. J Clin Gastroenterol 51:70-76|
|Graboyes, Evan M; Kallogjeri, Dorina; Saeed, Mohammed J et al. (2017) Postoperative care fragmentation and thirty-day unplanned readmissions after head and neck cancer surgery. Laryngoscope 127:868-874|
|Venable, Erin; Discepolo, Dakota; Powell, Ellie et al. (2017) An evaluation of current working canine decontamination procedures and methods for improvement. J Vet Behav 21:53-58|
|George, Ige A; Santos, Carlos A Q; Olsen, Margaret A et al. (2017) Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a Large Retrospective Cohort of Patients After Solid Organ Transplantation. Open Forum Infect Dis 4:ofx004|
|Liang, Stephen Y; Beekmann, Susan E; Polgreen, Philip M et al. (2016) Current Management of Cardiac Implantable Electronic Device Infections by Infectious Disease Specialists. Clin Infect Dis 63:1072-1075|
|Spataro, Emily; Piccirillo, Jay F; Kallogjeri, Dorina et al. (2016) Revision Rates and Risk Factors of 175?842 Patients Undergoing Septorhinoplasty. JAMA Facial Plast Surg 18:212-9|
|Yarbrough, Chester K; Bommarito, Kerry M; Gamble, Paul G et al. (2016) Population-based approaches to treatment and readmission after spinal cord injury. J Neurosurg Sci :|
Showing the most recent 10 out of 120 publications