The objectives of this study are: 1) to determine the optimal efficacious dose at which Trocade when administered against background therapy of MTX, a NSAID and corticosteroid (if required) prevents structural damage to articular joints; 2) to determine if Trocade when administered against background therapy can improve or stablize clinical signs and symptoms, disability or quality of life; 3) to determine the safety of Trocade when administered against background therapy of MTX and/or NSAID and/or steroids; 4) to investigate the pharmacokinetics of Trocade when administered against background therapy.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
3M01RR000046-39S2
Application #
6263885
Study Section
Project Start
1998-12-01
Project End
1999-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
39
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
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