The objective of this study is to access renal function in renal transplant patients. Here kidney function is determined by administering renal markers--PAH, Iothalamate and Cephalexin to renal transplant patients to study active tubular anionic secretion, filtration, and active tubular secretion. Twelve kidney transplant patients will be divided into two groups, six will receive Iothalamate (IOH) and PAH over a three hour period, the other six will receive Cephalexin as a bolus and studied over eight hours. Drugs will be assayed in plasma and urine collected, and results compared with six normals receiving Ioth/PAH.

Project Start
2000-12-01
Project End
2001-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2001
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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