This study will examine the effects of experimentally-induced metabolic acidosis on the synthesis of protein in muscle biopsy samples obtained before and after a bout of resistance exercise. Each subject will be evaluated twice. On one admission they will received NH4CL to induce acidosis, on the other placebo. The difference in muscle synthesis rates in the exercised and non-exercised limb will be compared under acidotic and normal conditions to test the hypothesis that acidosis will limit the anabolic response to exercise.

Project Start
1999-12-01
Project End
2000-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
38
Fiscal Year
2000
Total Cost
$564
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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