The overall goal of the General Clinical Research Center (GCRC) at Baylor College of Medicine is to providean environment for patient-oriented research which leads to an improved understanding of various diseaseprocesses, allows for better methods of treatment and diagnosis, offers training for clinical investigators, andfacilitates the collaboration of investigators conducting clinical research.The GCRC supports studies ranging from Pediatrics, Medicine, Allergy/Immunology, Genetics, Obstetricsand Gynecology, Surgery, Neonatology, Cell and Gene Therapy, Hematology/Oncology, Endocrinology,Infectious Disease, Neurology, Gastroenterology, and Nutrition. Each protocol submission must have IRBapproval and undergo a review by the GCRC Scientific Advisory Committee focusing on scientific merit,study design, analysis and patient safety. Once approved by the Committee, an investigator can utilize theGCRC and its resources.The General Clinical Research Center at Baylor College of Medicine has been open at Texas Children'sHospital and supported through the NCRR at NIH for 41 years. The GCRC is structured to accommodatepatient-oriented research activities at appropriate sites throughout various departments of Baylor College ofMedicine. A single administrative structure supports both the Pediatric and Adult Units of the GCRC. ThePediatric Unit at Texas Children's Hospital includes a discrete inpatient unit consisting of six patient beds, anoutpatient clinic, specialized Neonatal Research Satellite Unit located within the neonatal intensive care unit,as well as a gene therapy core laboratory available to both the pediatric and adult units. The Adult SatelliteUnit consists of a per diem unit within The Methodist Hospital as well as adult outpatient facilities located onthe 12th floor of the Baylor Clinic building.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR000188-44
Application #
7356044
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Program Officer
Merchant, Carol
Project Start
1997-01-06
Project End
2011-11-30
Budget Start
2007-12-01
Budget End
2008-11-30
Support Year
44
Fiscal Year
2008
Total Cost
$2,624,901
Indirect Cost
Name
Baylor College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Michalsky, Marc P; Inge, Thomas H; Jenkins, Todd M et al. (2018) Cardiovascular Risk Factors After Adolescent Bariatric Surgery. Pediatrics 141:
Lau, Chantal (2018) Breastfeeding Challenges and the Preterm Mother-Infant Dyad: A Conceptual Model. Breastfeed Med 13:8-17
Hunsaker, Sanita L; Garland, Beth H; Rofey, Dana et al. (2018) A Multisite 2-Year Follow Up of Psychopathology Prevalence, Predictors, and Correlates Among Adolescents Who Did or Did Not Undergo Weight Loss Surgery. J Adolesc Health 63:142-150
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Gururangan, Sridharan; Reap, Elizabeth; Schmittling, Robert et al. (2017) Regulatory T cell subsets in patients with medulloblastoma at diagnosis and during standard irradiation and chemotherapy (PBTC N-11). Cancer Immunol Immunother 66:1589-1595
Lanzieri, T M; Leung, J; Caviness, A C et al. (2017) Long-term outcomes of children with symptomatic congenital cytomegalovirus disease. J Perinatol 37:875-880
El-Hattab, Ayman W; Zarante, Ana Maria; Almannai, Mohammed et al. (2017) Therapies for mitochondrial diseases and current clinical trials. Mol Genet Metab 122:1-9
Jin, Haoxing Douglas; Demmler-Harrison, Gail J; Coats, David K et al. (2017) Long-term Visual and Ocular Sequelae in Patients With Congenital Cytomegalovirus Infection. Pediatr Infect Dis J 36:877-882
Oh, Sam S; Du, Randal; Zeiger, Andrew M et al. (2017) Breastfeeding associated with higher lung function in African American youths with asthma. J Asthma 54:856-865

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