Leucine is a branched-chain essential amino acid. Its metabolism is linked to that of alanine and glucose. In pregnancy, the rate of gluconeogenesis is low, suggesting that muscle glycolysis should also be low, implying that glucose is spared for the fetus. The purpose of this protocol is to evaluate the question of where the mother gets her energy. Subject population consists of normal and diabetic pregnancies, and those complicated by intrauterine growth retardation.

Project Start
Project End
Budget Start
Budget End
Support Year
25
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
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