This is a pilot study to obtain preliminary data on the safety and efficacy of sertraline treatment for depressed patients in the early acute post-myocardial infarction period. Four to ten patients meeting criteria for major depressive episode 5-21 days after acute myocardial infarction will be treated in open label fashion with sertraline. Psychosocial, Holter monitor, electrocardiographic, radionuclide ventriculography, and laboratory tests will be obtained at baseline and at intervals throughout the treatment.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000645-25A1
Application #
5221064
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
25
Fiscal Year
1996
Total Cost
Indirect Cost
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