This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. (from CRISP website) This study investigates early social and physiological processes involved in the development of self regulation and its relation to infant-mother attachment and cognitive development in high-risk infants. The research follows infants from hospital discharge until they are 2 years (corrected for gestational age). The study has 4 specific aims: (1) to examine 3 preverbal predictors of high risk infants' self-regulation, including neurophysiological modulation (early cardiorespiratory processes), quality of mutual regulation (parent-infant interaction), and infant self regulatory disposition (temperament), (2) to investigate parent-infant interaction quality over time as a mediator of the relation between infant/maternal characteristics and infants' cognitive and social outcomes, (3) to identify whether infants varying in risk levels and temperament are susceptible to negative parenting associated with chronic maternal depression, and (4) to identify relations among attachment, cognitive abilities, and self-regulation in high risk infants.
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