Alopecia Areata is a fairly common disease in which hair is lost either from part of the scalp, all of the scalp or the entire body. In some cases the disease is hereditary. It is thought to be an autoimmune disease. The Alopecia Areata Registry will collect clinically well characterized patients with these three forms of Alopecia Areata, alopecia areata (patchy loss of the scalp hair), alopecia totalis (total loss of all scalp hair) and alopecia universalis (complete loss of all hair everywhere on the body). This will be a collection of patients both in multi generational families and in sib pairs with controls. These well characterized patients will be used to search the human genome for disease associated loci and/or genes and a mechanism will be put in place to allow researchers interested in doing pathophysiology or treatment studies of this disease to be put in contact with patients having the appropriate form of the disease for the studies in question.

Project Start
2000-09-28
Project End
2005-09-29
Budget Start
2000-09-28
Budget End
2001-09-29
Support Year
Fiscal Year
2000
Total Cost
$583,870
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Internal Medicine/Medicine
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Litvinov, Ivan V; Tetzlaff, Michael T; Rahme, Elham et al. (2015) Identification of geographic clustering and regions spared by cutaneous T-cell lymphoma in Texas using 2 distinct cancer registries. Cancer 121:1993-2003
Swartz, Michael D; Kimmel, Marek; Mueller, Peter et al. (2006) Stochastic search gene suggestion: a Bayesian hierarchical model for gene mapping. Biometrics 62:495-503
Martinez-Mir, Amalia; Zlotogorski, Abraham; Ott, Jurg et al. (2003) Genetic linkage studies in alopecia areata. J Investig Dermatol Symp Proc 8:199-203
Barahmani, Nazila; Barahamani, Nazila; de Andrade, Mariza et al. (2002) Interleukin-1 receptor antagonist allele 2 and familial alopecia areata. J Invest Dermatol 118:335-7