The goal of this project is to evaluate the chronic toxicity and carcinogenicity of sodium tungstate dihydrate (STD) in rats and mice exposed via exposure in drinking water. Tungsten is a high production volume metal that is used in a variety of commercial applications, including military applications as a replacement for lead in small caliber ammunition and as a substitute for depleted uranium in armor penetrators. In addition, tungsten is found in dietary supplements and has potential clinical use as an antidiabetic therapy. 2-Year chronic toxicity and carcinogenicity studies of STD are in the in life phase. Keywords: toxicity, carcinogenicity, drinking water, sodium tungstate dihydrate

Agency
National Institute of Health (NIH)
Type
Research and Development Contracts (N01)
Project #
N01ES55541-19-0-8
Application #
8602486
Study Section
Project Start
2005-05-01
Project End
2013-04-30
Budget Start
Budget End
Support Year
Fiscal Year
2013
Total Cost
$693,887
Indirect Cost
Name
Battelle Centers/Pub Health Research & Evaluatn
Department
Type
DUNS #
007901598
City
Columbus
State
OH
Country
United States
Zip Code
43201