Project #3 - Intergenerational Processes and Aging in Multiple Generations This project's main goal is to enhance a genealogical database, the Intergenerationally-Linked Aging Sample (ILAS), and use it to understand the role of non-genetic factors in the intergenerational transmission of longevity, focusing on family structure, parental socioeconomic status (SES), and environmental shocks. The ILAS data have been collected from printed family histories and genealogies and contain demographic information on 118,062 people born between 1577 and 1983.
Aim 1 : Enhance the ILAS by merging ecological and macroeconomic variables, including cause-specific mortality rates, annual weather variables, elevation, malaria, hookworm, crop production, and recession indicators. We will make the data publicly available and provide a visual tree of family histories.
Aim 2 : Investigate the intergenerational and multi-generational transmission of longevity over the past four centuries, whether (and why) intergenerational effects have changed over the centuries, the role of maternal versus paternal longevity, and how the intergenerational effect differs for men and women.
Aim 3 : Examine the effect on children's longevity of family structure such as children's age at parental deaths and the absence and marital status of parents in early life, and how long the familial effects can persist.
Aim 4 : Examine the effect of parental exposure to 1) weather shocks such as drought, flood and heat, 2) disease environments such as malaria, hookworm and epidemics, 3) economic hardships caused by historical recessions (e.g., the 1837 panic) and harvest failures on children's longevity.
Aim 5 : Investigate the significance of the timing and duration of the parental exposures in Aim 4 to ecological and macroeconomic conditions, how these effects persist over generations, and how these effects are associated with family structure. We also will explore the interactions between environmental and inheritable factors such as epigenetic modifications mediated by an environmental shock.
Aim 6 : Study how the mean and variance in life expectancy have changed over the centuries, and how these trends are related to changes in the influence of intergenerational transmission of longevity over time.
Aim 7 : Examine the significance of exposure to stress due to environmental shocks in determining children's longevity by comparing the children of Civil War veterans (Projects #1 and #2) and non-veterans'children (Project #3) born in similar years.

Public Health Relevance

By investigating the inheritance of human longevity across generations, this project will enhance our understanding of how individuals, communities, and society can promote health and prolong life. The findings will have implications for disease prevention, the alleviation of the effects of environmental shocks and economic recessions on health, investment on early-life conditions, and family structure.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
2P01AG010120-19A1
Application #
8740086
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-04-30
Support Year
19
Fiscal Year
2014
Total Cost
Indirect Cost
Name
National Bureau of Economic Research
Department
Type
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02138
Costa, Dora (2015) Health and the Economy in the United States, from 1750 to the Present. J Econ Lit 53:503-570
Lee, Chulhee (2015) Industrial Characteristics and Employment of Older Manufacturing Workers in the Early-Twentieth-Century United States. Soc Sci Hist 39:551-579
Costa, Dora L (2014) Leaders: Privilege, Sacrifice, Opportunity, and Personnel Economics in the American Civil War. J Law Econ Organ 30:437-462
Hong, Sok Chul (2013) Malaria: an early indicator of later disease and work level. J Health Econ 32:612-32
Fogel, Robert W; Cain, Louis; Burton, Joseph et al. (2013) Was what ail'd ya what kill'd ya? Econ Hum Biol 11:269-80
Costa, Dora L (2012) Scarring and mortality selection among Civil War POWs: a long-term mortality, morbidity, and socioeconomic follow-up. Demography 49:1185-206
Bleakley, Hoyt; Lin, Jeffrey (2012) Portage and Path Dependence. Q J Econ 127:587-644
Bleakley, Hoyt; Lin, Jeffrey (2012) Thick-Market Effects and Churning in the Labor Market: Evidence from U.S. Cities. J Urban Econ 72:87-103
Lee, Chulhee (2012) Military Service and Economic Mobility: Evidence from the American Civil War. Explor Econ Hist 49:367-379
Costa, Dora L; Kahn, Matthew E (2010) Health, wartime stress, and unit cohesion: evidence from Union Army veterans. Demography 47:45-66

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