PROVIDED. The Administrative Core's objective continues to be to coordinate and facilitate interactions between this program project's cores and projects. Core A will also provide efficient, responsible, and reliable administration of the program project with regard to all budgetary matters and communication among program participants. In addition, this core will provide program project investigators with the biostatistical support services of D. Songthip Ounpraseuth, PhD, a new collaborator with expertise in experimental design and statistical analysis. In this capacity, he replaces D. Keith Williams, PhD. The Administrative Core's specific aims are to: 1) provide management of the grant by facilitating necessary interactions among grants management officials at the National Institute on Aging (NIA), the University of Arkansas for Medical Sciences (UAMS), and the Imperial College School of Medicine (Imperial) in London;2) manage all budgetary matters concerning the grant's overall administration by assembling, collating, and processing all budget information from cores and projects and preparing and distributing budget reports to each of the core and project leaders;3) prepare the yearly progress report;4) make arrangements for all meetings of program participants;5) manage appropriate handling and mailing of samples to requesting investigators;6) coordinate the flow of information collected for yearly progress reports to appropriate program personnel;and 7) through the use of Dr. Ounpraseuth biostatistical services, provide statistical expertise for the design and interpretation of experiments in the projects and evaluate goals for the cores.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG012411-16
Application #
8446384
Study Section
Special Emphasis Panel (ZAG1-ZIJ-2)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
16
Fiscal Year
2013
Total Cost
$154,749
Indirect Cost
$52,099
Name
University of Arkansas for Medical Sciences
Department
Type
DUNS #
122452563
City
Little Rock
State
AR
Country
United States
Zip Code
72205
Lamture, Gauri; Crooks, Peter A; Borrelli, Michael J (2018) Actinomycin-D and dimethylamino-parthenolide synergism in treating human pancreatic cancer cells. Drug Dev Res 79:287-294
Kiaei, Mahmoud; Balasubramaniam, Meenakshisundaram; Govind Kumar, Vivek et al. (2018) ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation. Sci Rep 8:13102
Zafar, Maroof K; Maddukuri, Leena; Ketkar, Amit et al. (2018) A Small-Molecule Inhibitor of Human DNA Polymerase ? Potentiates the Effects of Cisplatin in Tumor Cells. Biochemistry 57:1262-1273
Janganati, Venumadhav; Ponder, Jessica; Balasubramaniam, Meenakshisundaram et al. (2018) MMB triazole analogs are potent NF-?B inhibitors and anti-cancer agents against both hematological and solid tumor cells. Eur J Med Chem 157:562-581
Ayyadevara, Srinivas; Ganne, Akshatha; Hendrix, Rachel D et al. (2018) Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'. J Neurosci Methods :
Balasubramaniam, Meenakshisundaram; Ayyadevara, Srinivas; Shmookler Reis, Robert J (2018) Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2. Sci Rep 8:14891
Liu, A K L; Lim, E J; Ahmed, I et al. (2018) Review: Revisiting the human cholinergic nucleus of the diagonal band of Broca. Neuropathol Appl Neurobiol 44:647-662
Balasubramaniam, Meenakshisundaram; Reis, Robert J Shmookler; Ayyadevara, Srinivas et al. (2017) Involvement of tRNAs in replication of human mitochondrial DNA and modifying effects of telomerase. Mech Ageing Dev 166:55-63
Barger, Steven W (2016) Gene regulation and genetics in neurochemistry, past to future. J Neurochem 139 Suppl 2:24-57
Mao, Xianrong; Phanavanh, Bounleut; Hamdan, Hamdan et al. (2016) NF?B-inducing kinase inhibits NF?B activity specifically in neurons of the CNS. J Neurochem 137:154-63

Showing the most recent 10 out of 140 publications