The main functions of the Administrative Core are to: a) facilitate distribution of research materials and resources to the various investigators;b) facilitate communication between investigators, cores the advisory committees, affiliated institutions and the funding agency;c) evaluate the quality of ongoing research as well as programs to be considered for future expansion;d) cut brain tissue specimens and harvest frozen specimens for distribution, in a blinded fashion for investigators;d) interact with Core B and e) maintain a web page for the PPG. Core A functions will be accomplished with the help of three different committees: 1) the Internal Advisory group consisting of project and core leaders. It will meet on a monthly basis to discuss research projects, protocols, results and any problems that might arise in this collaborative effort. The External Advisory Committee which consists of scientists with expertise in various disciplines represented in this application will meet with Internal Advisory Committee every other a year. In the off years there will be video conferences. It will review progress and advise on the overall quality of the work. Meeting will be chaired by the Core leader. Dr. Mufson. These meetings will provide a forum for discussing new ideas and a mechanism for expanding the program with worthy projects in the future. The Administrative Core will be led by the Principal Investigator and Co-PL of the Core.
A centralized Administrative Core is a necessity for the daily function of the entire program project since it the PPG brings together investigators from three NIA funded Alzheimer's disease center. The core coordinates budgetary and organization issues as well as transfers and tracks tissue specimens provided for each subproject.
|Kelly, Sarah C; He, Bin; Perez, Sylvia E et al. (2017) Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease. Acta Neuropathol Commun 5:8|
|McKay, Erin; Counts, Scott E (2017) Multi-Infarct Dementia: A Historical Perspective. Dement Geriatr Cogn Dis Extra 7:160-171|
|Perez, Sylvia E; Nadeem, Muhammad; Malek-Ahmadi, Michael H et al. (2017) Frontal Cortex and Hippocampal ?-Secretase Activating Protein Levels in Prodromal Alzheimer Disease. Neurodegener Dis 17:235-241|
|Marquié, Marta; Normandin, Marc D; Meltzer, Avery C et al. (2017) Pathological correlations of [F-18]-AV-1451 imaging in non-alzheimer tauopathies. Ann Neurol 81:117-128|
|Ikonomovic, Milos D; Mi, Zhiping; Abrahamson, Eric E (2017) Disordered APP metabolism and neurovasculature in trauma and aging: Combined risks for chronic neurodegenerative disorders. Ageing Res Rev 34:51-63|
|Krivinko, Josh M; Erickson, Susan L; Abrahamson, Eric E et al. (2017) Kalirin reduction rescues psychosis-associated behavioral deficits in APPswe/PSEN1dE9 transgenic mice. Neurobiol Aging 54:59-70|
|Sorrentino, Vincenzo; Romani, Mario; Mouchiroud, Laurent et al. (2017) Enhancing mitochondrial proteostasis reduces amyloid-? proteotoxicity. Nature 552:187-193|
|Mahady, Laura J; Perez, Sylvia E; Emerich, Dwaine F et al. (2017) Cholinergic profiles in the Goettingen miniature pig (Sus scrofa domesticus) brain. J Comp Neurol 525:553-573|
|Counts, Scott E; Mufson, Elliott J (2017) Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease. Cell Transplant 26:693-702|
|Powers, Brian E; Kelley, Christy M; Velazquez, Ramon et al. (2017) Maternal choline supplementation in a mouse model of Down syndrome: Effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring. Neuroscience 340:501-514|
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