We propose a Program of Projects to advance the applied science of evaluating health-related quality of life (HRQOL) in older U.S. adults. We simultaneously use four widely-used generic HRQOL instruments, the SF-36v2, EuroQol EQ-5D, Quality of Well-being scale (QWB-SA), and Health Utilities Index (HUI2/3). Additionally we use the HALex from the National Center for Health Statistics. Project 1 uses a telephone survey to interview a cross-sectional sample of 2800 non-institutionalized adult U.S. residents aged 35-89. Persons aged 65 and older will be over-sampled to provide higher precision in older ages. African Americans are over-sampled for the first national survey of substantial size (n=1000) of this important sub-population. Project 1 data will be used to construct gender- and age-specific national reference averages for HRQOL among older adults on all measures. Project 2 will use all four measures to follow treatment and 6 month recovery of patients with three age-related diseases stressing different aspects of HRQOL newly referred congestive heart failure, hip replacement for osteoarthritis, and cataract extraction. This project will establish characteristics of the measures for longitudinal follow-up of patients with self-administered questionnaires. Project 3 examines how duration of a health condition affects HRQOL assessments and how this affects interpretation of HRQOL scores from standardized indexes. This is particularly important in the elderly as medical care increasingly prolongs life with chronic conditions. Project 4 determines survey mode effects (telephone versus self-administration) for all instruments as well as English versus Spanish language administration for persons who are usually Spanish speakers. The Program will enhance health researchers' ability to measure, follow, and interpret HRQOL in adults and to assess health disparities.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG020679-03
Application #
7090022
Study Section
Special Emphasis Panel (ZAG1-ZIJ-1 (J2))
Program Officer
Nielsen, Lisbeth
Project Start
2004-09-15
Project End
2008-06-30
Budget Start
2006-07-01
Budget End
2007-06-30
Support Year
3
Fiscal Year
2006
Total Cost
$1,705,040
Indirect Cost
Name
University of Wisconsin Madison
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Assari, Shervin (2016) Psychosocial Correlates of Body Mass Index in the United States: Intersection of Race, Gender and Age. Iran J Psychiatry Behav Sci 10:e3458
Hanmer, Janel; Cherepanov, Dasha; Palta, Mari et al. (2016) Health Condition Impacts in a Nationally Representative Cross-Sectional Survey Vary Substantially by Preference-Based Health Index. Med Decis Making 36:264-74
Groessl, Erik J; Liu, Lin; Sklar, Marisa et al. (2013) Measuring the impact of cataract surgery on generic and vision-specific quality of life. Qual Life Res 22:1405-14
Sarkin, Andrew J; Groessl, Erik J; Carlson, Jordan A et al. (2013) Development and validation of a mental health subscale from the Quality of Well-Being Self-Administered. Qual Life Res 22:1685-96
Beaumont, Jennifer L; Havlik, Richard; Cook, Karon F et al. (2013) Norming plans for the NIH Toolbox. Neurology 80:S87-92
Sellers, Sherrill; Cherepanav, Dasha; Hanmer, Janel et al. (2013) Interpersonal discrimination and health-related quality of life among black and white men and women in the United States. Qual Life Res 22:1307-12
Palta, Mari (2013) Some comments on mapping from disease-specific to generic health-related quality-of-life scales. Value Health 16:211-4; discussion 217-8
Sellers, Sherrill L; Cherepanov, Dasha; Hanmer, Janel et al. (2013) Erratum to: Interpersonal discrimination and health-related quality of life among black and white men and women in the United States. Qual Life Res 22:1313-8
Varma, Rohit; McKean-Cowdin, Roberta; Vitale, Susan et al. (2013) Vision assessment using the NIH Toolbox. Neurology 80:S37-40
Maglinte, Gregory A; Hays, Ron D; Kaplan, Robert M (2012) US general population norms for telephone administration of the SF-36v2. J Clin Epidemiol 65:497-502

Showing the most recent 10 out of 52 publications