Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
2P01AG025532-06A1
Application #
8461014
Study Section
Special Emphasis Panel (ZAG1-ZIJ-2 (02))
Project Start
Project End
Budget Start
2012-12-15
Budget End
2013-11-30
Support Year
6
Fiscal Year
2013
Total Cost
$176,826
Indirect Cost
$51,753
Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Granatiero, Veronica; Patron, Maria; Tosatto, Anna et al. (2014) Using targeted variants of aequorin to measure Ca2+ levels in intracellular organelles. Cold Spring Harb Protoc 2014:86-93
Chen, Y; Hagopian, K; Bibus, D et al. (2014) The influence of dietary lipid composition on skeletal muscle mitochondria from mice following eight months of calorie restriction. Physiol Res 63:57-71
Tomilov, Alexey; Bettaieb, Ahmed; Kim, Kyoungmi et al. (2014) Shc depletion stimulates brown fat activity in vivo and in vitro. Aging Cell 13:1049-58
Patron, Maria; Checchetto, Vanessa; Raffaello, Anna et al. (2014) MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity. Mol Cell 53:726-37
Sahdeo, Sunil; Tomilov, Alexey; Komachi, Kelly et al. (2014) High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects. Mitochondrion 17:116-25
Logan, Clare V; Szabadkai, Gyorgy; Sharpe, Jenny A et al. (2014) Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling. Nat Genet 46:188-93
Granatiero, Veronica; Patron, Maria; Tosatto, Anna et al. (2014) The use of aequorin and its variants for Ca2+ measurements. Cold Spring Harb Protoc 2014:9-16
Stern, Jennifer H; Kim, Kyoungmi; Ramsey, Jon J (2014) The influence of shc proteins on the whole body energetic response to calorie restriction initiated in 3-month-old mice. ISRN Nutr 2014:562075
Bock, Fabian; Shahzad, Khurrum; Wang, Hongjie et al. (2013) Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc. Proc Natl Acad Sci U S A 110:648-53
Chen, Yana; Hagopian, Kevork; Bibus, Douglas et al. (2013) The influence of dietary lipid composition on liver mitochondria from mice following 1 month of calorie restriction. Biosci Rep 33:83-95

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