Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
1P01AG032131-01A1
Application #
7582811
Study Section
Special Emphasis Panel (ZAG1-ZIJ-7 (O2))
Project Start
2008-12-01
Project End
2011-11-30
Budget Start
2009-01-15
Budget End
2009-12-31
Support Year
1
Fiscal Year
2009
Total Cost
$254,069
Indirect Cost
Name
Carnegie-Mellon University
Department
Type
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Bereau, Tristan; Wang, Zun-Jing; Deserno, Markus (2014) More than the sum of its parts: coarse-grained peptide-lipid interactions from a simple cross-parametrization. J Chem Phys 140:115101
Gericke, Arne; Leslie, Nicholas R; Lösche, Mathias et al. (2013) PtdIns(4,5)P2-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanism. Adv Exp Med Biol 991:85-104
Lioudyno, Maria I; Birch, Alexandra M; Tanaka, Brian S et al. (2013) Shaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anesthetics. J Neurosci 33:16310-22
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Shenoy, Siddharth S; Nanda, Hirsh; Lösche, Mathias (2012) Membrane association of the PTEN tumor suppressor: electrostatic interaction with phosphatidylserine-containing bilayers and regulatory role of the C-terminal tail. J Struct Biol 180:394-408
Shenoy, Siddharth; Shekhar, Prabhanshu; Heinrich, Frank et al. (2012) Membrane association of the PTEN tumor suppressor: molecular details of the protein-membrane complex from SPR binding studies and neutron reflection. PLoS One 7:e32591
Zan, Goh Haw; Tan, Cheemeng; Deserno, Markus et al. (2012) Hemifusion of giant unilamellar vesicles with planar hydrophobic surfaces: a fluorescence microscopy study. Soft Matter 8:10877-10886
Lioudyno, Maria I; Broccio, Matteo; Sokolov, Yuri et al. (2012) Effect of synthetic aýý peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance. PLoS One 7:e35090
Bereau, Tristan; Deserno, Markus; Bachmann, Michael (2011) Structural basis of folding cooperativity in model proteins: insights from a microcanonical perspective. Biophys J 100:2764-72
Yaron, Peter N; Holt, Brian D; Short, Philip A et al. (2011) Single wall carbon nanotubes enter cells by endocytosis and not membrane penetration. J Nanobiotechnology 9:45

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