Specific aims of the Measurement and Study Coordination Core (Core B) involve facilitating comparative and replicable research based on coordinated or pooled-data analysis of longitudinal studies of aging. The focus is on developing tools and documentation to support the identification of relevant studies for answering particular questions and to enable rigorous cross-study comparison and data harmonization activities. A purpose-built website enabling organization and aggregation of study and measurement related information will be created (SA1, infrastructure/tools) by the International Harmonization Platform (IHP) team, adapting as necessary the methods, web-based tools and software developed by this group of experts. The website will include and provide access to an extensive searchable cross-study catalogue (SA2, content) for organizing and comparing information about the variables collected by each study, and a contextual database (SA3, content) that will include historical country (or in limited cases region) level information that can be used in addressing cross-national heterogeneity in parallel and pooled analyses. The contextual database will initially be focused on major health and mortality characteristics, average physical height, and standard educational attainment over the range of birth cohorts represented in the lALSA and HALCyon networks. The website will also include a framework to assist in management of all steps of the data harmonization process (SA4, harmonization activities). The website developed by this core will provide a central communication portal for investigators involved in the proposed analyses of affiliated datasets and will include tracking of permissions for data usage from collaborating studies, project management, and a record of published and in progress manuscripts (managed by Core A).

Public Health Relevance

This Core represents the central resources and activities related to creating an international harmonization platform for longitudinal studies of aging. It will provide key support to the subprojects that make up this program project and will furnish essential resources to all researchers eingaged in collaborative interdisciplinary research using data collected in major longitudinal studies on aging.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG043362-02
Application #
8667970
Study Section
Special Emphasis Panel (ZAG1-ZIJ-9)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
2
Fiscal Year
2014
Total Cost
$489,114
Indirect Cost
$4,192
Name
Oregon Health and Science University
Department
Type
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Bendayan, Rebecca; Cooper, Rachel; Wloch, Elizabeth G et al. (2016) Hierarchy and Speed of Loss in Physical Functioning: A Comparison Across Older U.S. and English Men and Women. J Gerontol A Biol Sci Med Sci :
Stephan, Blossom C M; Tang, Eugene; Muniz-Terrera, Graciela (2016) Composite risk scores for predicting dementia. Curr Opin Psychiatry 29:174-80
Cadar, Dorina; Stephan, Blossom C M; Jagger, Carol et al. (2016) The role of cognitive reserve on terminal decline: a cross-cohort analysis from two European studies: OCTO-Twin, Sweden, and Newcastle 85+, UK. Int J Geriatr Psychiatry 31:601-10
Kelly, Amanda; Calamia, Matthew; Koval, Andrey et al. (2016) Independent and interactive impacts of hypertension and diabetes mellitus on verbal memory: A coordinated analysis of longitudinal data from England, Sweden, and the United States. Psychol Aging 31:262-73
Cooper, Rachel; Muniz-Terrera, Graciela; Kuh, Diana (2016) Associations of behavioural risk factors and health status with changes in physical capability over 10 years of follow-up: the MRC National Survey of Health and Development. BMJ Open 6:e009962
Praetorius Björk, Marcus; Johansson, Boo; Hassing, Linda B (2016) I forgot when I lost my grip-strong associations between cognition and grip strength in level of performance and change across time in relation to impending death. Neurobiol Aging 38:68-72
Ramsey, Jennifer L; Neupert, Shevaun D; Mroczek, Daniel K et al. (2016) The effects of daily co-occurrence of affect on older adults' reactivity to health stressors. Psychol Health 31:364-78
Brown, Cassandra L; Robitaille, Annie; Zelinski, Elizabeth M et al. (2016) Cognitive activity mediates the association between social activity and cognitive performance: A longitudinal study. Psychol Aging 31:831-846
Leszko, Magdalena; Elleman, Lorien G; Bastarache, Emily D et al. (2016) Future Directions in the Study of Personality in Adulthood and Older Age. Gerontology 62:210-5
Muniz-Terrera, Graciela; Robitaille, Annie; Kelly, Amanda et al. (2016) Latent growth models matched to research questions to answer questions about dynamics of change in multiple processes. J Clin Epidemiol :

Showing the most recent 10 out of 38 publications