Abstract

The administrative core will continue to support ongoing research and help to promote research synergy among members ofthe PPG. The core will continue to provide assistance with grant/manuscript preparation, administrative and tinancial support and establish mechanisms to ensure quality control and efficient usage of PPG resources. Research and administrative meetings will be scheduled at regular intervals to discuss progress and problems. The core will organize meetings of the internal advisory committee to insure appropriate oversight ofthe program. In addition, the core will organize and provide logistical support for an annual meeting with the external advisory committee and will organize the biodefense seminar series supported by this grant. This core will also provide statistical support for experimental design and data analysis for each ofthe projects. Day-to-day administrative support for grants management, purchase requisitions, animal care compliance, safety compliance, manuscript and reporting activities will also be provided to PPG members. Overall, the administrative core will continue to provide essential support services in orderto help foster the ongoing success ofthe Program.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI056172-09
Application #
8728382
Study Section
Special Emphasis Panel (ZAI1-PA-I)
Project Start
Project End
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
9
Fiscal Year
2014
Total Cost
$131,526
Indirect Cost
$38,279

  Institution

Name
University of Connecticut
Department
Type
DUNS #
022254226
City
Farmington
State
CT
Country
United States
Zip Code
06030

  Publications

Benoun, Joseph M; Peres, Newton G; Wang, Nancy et al. (2018) Optimal protection against Salmonella infection requires noncirculating memory. Proc Natl Acad Sci U S A 115:10416-10421
Ménoret, Antoine; Buturla, James A; Xu, Maria M et al. (2018) T cell-directed IL-17 production by lung granular ?? T cells is coordinated by a novel IL-2 and IL-1? circuit. Mucosal Immunol 11:1398-1407
Shinde, Paurvi; Liu, Wenhai; Ménoret, Antoine et al. (2017) Optimal CD4 T cell priming after LPS-based adjuvanticity with CD134 costimulation relies on CXCL9 production. J Leukoc Biol 102:57-69
Liu, Wenhai; Menoret, Antoine; Vella, Anthony T (2017) Responses to LPS boost effector CD8 T-cell accumulation outside of signals 1 and 2. Cell Mol Immunol 14:254-253
Lee, Seung-Joo; Benoun, Joseph; Sheridan, Brian S et al. (2017) Dual Immunization with SseB/Flagellin Provides Enhanced Protection against Salmonella Infection Mediated by Circulating Memory Cells. J Immunol 199:1353-1361
Romagnoli, P A; Fu, H H; Qiu, Z et al. (2017) Differentiation of distinct long-lived memory CD4 T cells in intestinal tissues after oral Listeria monocytogenes infection. Mucosal Immunol 10:520-530
Pham, Oanh H; O'Donnell, Hope; Al-Shamkhani, Aymen et al. (2017) T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria. PLoS Pathog 13:e1006566
Risso, Gabriela S; Carabajal, Marianela V; Bruno, Laura A et al. (2017) U-Omp19 fromBrucella abortusIs a Useful Adjuvant for Vaccine Formulations againstSalmonellaInfection in Mice. Front Immunol 8:171
Svedova, Julia; Ménoret, Antoine; Mittal, Payal et al. (2017) Therapeutic blockade of CD54 attenuates pulmonary barrier damage in T cell-induced acute lung injury. Am J Physiol Lung Cell Mol Physiol 313:L177-L191
Benoun, Joseph M; Labuda, Jasmine C; McSorley, Stephen J (2016) Collateral Damage: Detrimental Effect of Antibiotics on the Development of Protective Immune Memory. MBio 7:

Showing the most recent 10 out of 87 publications