The function of this Core A will be to provide administrative support, oversight and efficient management of this PPG application with the overarching goal of ensuring the scientific progress and coordination of all projects. The Core will be directed by Dr. Ihaki Sanz (overall P.L, and Project 2 Leader). The Administrative Core will coordinate the inter-project, inter-departmental collaborative arrangements and arrangements between the University of Rochester and collaborators at UC Berkeley (Dr. Hellerstein, heavy water experiments) and UT Southwestern (Dr. Scheuermann, flow cytometry FLOCK analysis). The Administrative Core will also provide the Projects and Cores with a review of all expenditures on a monthly basis and will deal with University Accounting and Grants management offices concerning grant budgets. The administrative support provided by the Administrative Core will reconcile all budgets of the Projects and Cores, and oversee compliance with regulatory issues. For example. Core A will maintain direct linkages to the University Office of the Vice Dean for Research (Dr. Ed Puzas). These links will be used to keep an accounting of the funding and expenditures for the purpose of annual progress reports. In addition, the Administrative Core will be responsible for organizing meetings and seminars of the PPG investigators, as well as the meetings of the External Advisory Committee as outlined below.

Public Health Relevance

The function of this Core A will be to provide administrative support, oversight and efficient management of this PPG application with the overarching goal of ensuring the scientific progress and coordination of all projects.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI078907-05
Application #
8707318
Study Section
Special Emphasis Panel (ZAI1-PA-I)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
5
Fiscal Year
2014
Total Cost
$178,242
Indirect Cost
$21,710
Name
Emory University
Department
Type
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Meednu, Nida; Zhang, Hengwei; Owen, Teresa et al. (2016) Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis. Arthritis Rheumatol 68:805-16
Rahimi, Homaira; Bell, Richard; Bouta, Echoe M et al. (2016) Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential. Arthritis Res Ther 18:194
Kuzin, Igor I; Kates, Stephen L; Ju, Yawen et al. (2016) Increased numbers of CD23(+) CD21(hi) Bin-like B cells in human reactive and rheumatoid arthritis lymph nodes. Eur J Immunol 46:1752-7
Newell, K A; Asare, A; Sanz, I et al. (2015) Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients. Am J Transplant 15:2908-20
Adlowitz, Diana G; Barnard, Jennifer; Biear, Jamie N et al. (2015) Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response. PLoS One 10:e0128269
Bird, Anna K; Meednu, Nida; Anolik, Jennifer H (2015) New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndrome. Curr Opin Rheumatol 27:461-7
Wilmore, Joel R; Asito, Amolo S; Wei, Chungwen et al. (2015) AID expression in peripheral blood of children living in a malaria holoendemic region is associated with changes in B cell subsets and Epstein-Barr virus. Int J Cancer 136:1371-80
Halliley, Jessica L; Tipton, Christopher M; Liesveld, Jane et al. (2015) Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow. Immunity 43:132-45
Bouta, Echoe M; Li, Jie; Ju, Yawen et al. (2015) The role of the lymphatic system in inflammatory-erosive arthritis. Semin Cell Dev Biol 38:90-7
Wei, Chungwen; Jenks, Scott; Sanz, Iñaki (2015) Polychromatic flow cytometry in evaluating rheumatic disease patients. Arthritis Res Ther 17:46

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