1 of WHP-San Francisco, serves as Director of the Gladstone Institute of Virology and Immunology. 16. LETTERS OF SUPPORT (e.g., Consultants) A letter from Dr. Mark Scott, who will provide technical expertise in regards to the handling of endocervical samples using the Luminex platform, is enclosed on page 133. 17. RESOURCE SHARING A major benefit of scientific research is its potential translation for the benefit of human health. Rapid sharing of scientific data and reagents/resources can potentially reduce the time between a discovery and the effective """"""""translation"""""""" of that discovery. Scientific publications are the major mechanism for sharing data with other scientists and with the public at large. WHP-San Francisco investigators will make their published work available to interested scientists by submitting an electronic version of their paper to the National Library of Medicine's PubMed Central upon acceptance for publication. These papers will be made publicly available no later than 12 months after the official date of publication in accord with NIH Public Access Policy (NOT-OD-05-022). Similarly, reagents utilized in these publications will be made freely available to other academic investigators in a timely manner. The sharing of data and resources serves the best interest of overall scientific progress. When appropriate, patent protection may be sought for discoveries that may have commercial value. However, patenting procedures should not preclude the distribution of information or reagents to interested academic investigators, as outlined in the NIH Guidelines for Dissemination of Research Resources Arising Out of NIH-funded Research. WHP-San Francisco is dedicated to establishing the appropriate policies and procedures as a well as a culture for effective sharing of data and resources. Sharing Model Organisms: Development of model organisms is not planned in the current scope of work for WHP-San Francisco. Genome-Wide Association Studies (GWASj: Following publication of findings, microarray data generated in

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Roan, Nadia R; Sandi-Monroy, Nathallie; Kohgadai, Nargis et al. (2017) Semen amyloids participate in spermatozoa selection and clearance. Elife 6:
Smith-McCune, K K; Hilton, J F; Shanmugasundaram, U et al. (2017) Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility. Mucosal Immunol 10:1270-1278
Chen, Joseph C; Hoffman, Jacquelyn R; Arora, Ripla et al. (2016) Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity. Fertil Steril 105:501-10.e1
Shanmugasundaram, Uma; Hilton, Joan F; Critchfield, J William et al. (2016) Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. Am J Reprod Immunol 76:137-48
Goldfien, Gabriel A; Barragan, Fatima; Chen, Joseph et al. (2015) Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix. Reprod Sci 22:814-28
Oh, Sam S; Galanter, Joshua; Thakur, Neeta et al. (2015) Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled. PLoS Med 12:e1001918
Smith-McCune, Karen; Chen, Joseph C; Greenblatt, Ruth M et al. (2015) Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One 10:e0129769
Gesner, Marianne; Maiti, Mekhala; Grant, Robert et al. (2014) Fluorescence-linked Antigen Quantification (FLAQ) Assay for Fast Quantification of HIV-1 p24(Gag). Bio Protoc 4:
Cavrois, Marielle; Neidleman, Jason; Greene, Warner C (2014) HIV-1 Fusion Assay. Bio Protoc 4:
Roan, Nadia R; Liu, Haichuan; Usmani, Shariq M et al. (2014) Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection. J Virol 88:7221-34

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