To provide organizational structure for the entire PPG, we propose an Administrative Core designed to give leadership, oversight, and direction for the individual projects and scientific cores.
The specific aims for this core are as follows. The first specific aim is to set and implement the programmatic goals for the PPG through regular interactions with each of the participants in this PPG. An important function of this aim will be to monitor the progress of each project and reinforce the specific aims described in this proposal.
The second aim i s to assure effective communication among the participants of this project. This will be achieved by ensuring that the lines of communication between each of the project and core leaders remain strong.
Aim 3 will be to develop the scientific program by pursuing new funding avenues that will help in the development of our program. To ensure that all budgetary issues related to this PPG are handled appropriately, the fourth aim will be to maintain a system for fiscal accountability and resource allocation. This will be achieved by making use of trained personnel within our department who are experienced with NIH and UNMC policies related to grants administration. Finally, the fifth aim will be to provide statistical support for all projects in the planning of experiments and interpretation of results.
This final aim will support all four projects through regular meetings with the participants of this PPG. Ultimately, the achievement of these aims will assure maximum productivity of our group and will foster the success of this PPG.
|Ibberson, Carolyn B; Parlet, Corey P; Kwiecinski, Jakub et al. (2016) Hyaluronan Modulation Impacts Staphylococcus aureus Biofilm Infection. Infect Immun 84:1917-29|
|Marshall, Darrell D; Sadykov, Marat R; Thomas, Vinai C et al. (2016) Redox Imbalance Underlies the Fitness Defect Associated with Inactivation of the Pta-AckA Pathway in Staphylococcus aureus. J Proteome Res 15:1205-12|
|Kavanaugh, Jeffrey S; Horswill, Alexander R (2016) Impact of Environmental Cues on Staphylococcal Quorum Sensing and Biofilm Development. J Biol Chem 291:12556-64|
|Gries, Casey M; Sadykov, Marat R; Bulock, Logan L et al. (2016) Potassium Uptake Modulates Staphylococcus aureus Metabolism. mSphere 1:|
|Windham, Ian H; Chaudhari, Sujata S; Bose, Jeffrey L et al. (2016) SrrAB Modulates Staphylococcus aureus Cell Death through Regulation of cidABC Transcription. J Bacteriol 198:1114-22|
|Chaudhari, Sujata S; Thomas, Vinai C; Sadykov, Marat R et al. (2016) The LysR-type transcriptional regulator, CidR, regulates stationary phase cell death in Staphylococcus aureus. Mol Microbiol 101:942-53|
|Vidlak, Debbie; Kielian, Tammy (2016) Infectious Dose Dictates the Host Response during Staphylococcus aureus Orthopedic-Implant Biofilm Infection. Infect Immun 84:1957-65|
|Paharik, Alexandra E; Horswill, Alexander R (2016) The Staphylococcal Biofilm: Adhesins, Regulation, and Host Response. Microbiol Spectr 4:|
|Schaeffer, Carolyn R; Hoang, Tra-My N; Sudbeck, Craig M et al. (2016) Versatility of Biofilm Matrix Molecules in Staphylococcus epidermidis Clinical Isolates and Importance of Polysaccharide Intercellular Adhesin Expression during High Shear Stress. mSphere 1:|
|Lewis, April M; Rice, Kelly C (2016) Quantitative Real-Time PCR (qPCR) Workflow for Analyzing Staphylococcus aureus Gene Expression. Methods Mol Biol 1373:143-54|
Showing the most recent 10 out of 89 publications