The goal of the Administrative Core is to provide scientific leadership and organizational support to facilitate the research collaborations outlined in the application. This will be accomplished through five specific aims. I. Provide scientific leadership to program participants and monitor timelines to ensure progress. II. Provide coordination and facilitate interactions among all program participants. III. Recruit Scientific Advisory Board members and coordinate annual meetings. IV. Provide fiscal and contractual management to ensure efficient interactions among participant institutions. V. Provide administrative support for program activities including report preparation, intellectual property filings, publications, meeting arrangements and data sharing.

Public Health Relevance

Finding a vaccine for HIV is probably one of the most important goals of biomedical research. SIV challenge of vaccinated Indian rhesus macaques is one of the best defined models available for pre-clinical development of HIV vaccines.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI094420-03
Application #
8688138
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Type
DUNS #
City
Coral Gables
State
FL
Country
United States
Zip Code
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Shin, Young C; Bischof, Georg F; Lauer, William A et al. (2018) A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products. PLoS Pathog 14:e1007143
Magnani, Diogo M; Ricciardi, Michael J; Bailey, Varian K et al. (2017) Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys. Mol Ther 25:2323-2331
Magnani, Diogo M; Rogers, Thomas F; Beutler, Nathan et al. (2017) Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques. Sci Transl Med 9:
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