Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Program Projects (P01)
Project #
5P01AR041637-12
Application #
6749469
Study Section
Special Emphasis Panel (ZAR1-RJB-B (J1))
Program Officer
Nuckolls, Glen H
Project Start
1992-09-30
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
12
Fiscal Year
2004
Total Cost
$1,673,128
Indirect Cost
Name
Boston Biomedical Research Institute
Department
Type
DUNS #
058893371
City
Watertown
State
MA
Country
United States
Zip Code
02472
Guo, Hongqiu; Huang, Renjian; Semba, Shingo et al. (2013) Ablation of smooth muscle caldesmon affects the relaxation kinetics of arterial muscle. Pflugers Arch 465:283-94
Mabuchi, Yasuko; Mabuchi, Katsuhide; Stafford, Walter F et al. (2010) Modular structure of smooth muscle Myosin light chain kinase: hydrodynamic modeling and functional implications. Biochemistry 49:2903-17
Gali?ska, Agnieszka; Hatch, Victoria; Craig, Roger et al. (2010) The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments. Circ Res 106:705-11
Hayes, David; Napoli, Vanessa; Mazurkie, Andrew et al. (2009) Phosphorylation dependence of hsp27 multimeric size and molecular chaperone function. J Biol Chem 284:18801-7
Mudalige, Wasana A K A; Tao, Terence C; Lehrer, Sherwin S (2009) Ca2+-dependent photocrosslinking of tropomyosin residue 146 to residues 157-163 in the C-terminal domain of troponin I in reconstituted skeletal muscle thin filaments. J Mol Biol 389:575-83
Greenberg, M J; Wang, C-L A; Lehman, W et al. (2008) Modulation of actin mechanics by caldesmon and tropomyosin. Cell Motil Cytoskeleton 65:156-64
Coulton, Arthur T; Koka, Kezia; Lehrer, Sherwin S et al. (2008) Role of the head-to-tail overlap region in smooth and skeletal muscle beta-tropomyosin. Biochemistry 47:388-97
Sumida, John P; Wu, Eleanor; Lehrer, Sherwin S (2008) Conserved Asp-137 imparts flexibility to tropomyosin and affects function. J Biol Chem 283:6728-34
Wang, C L Albert (2008) Caldesmon and the regulation of cytoskeletal functions. Adv Exp Med Biol 644:250-72
Lee, Eunhee; Hayes, David B; Langsetmo, Knut et al. (2007) Interactions between the leucine-zipper motif of cGMP-dependent protein kinase and the C-terminal region of the targeting subunit of myosin light chain phosphatase. J Mol Biol 373:1198-212

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