The Clinical Research Core will serve as a scientific resource to each of the individual components of the Stanford CAM Center for Chronic Back Pain, advancing the scientific aims fo the Center by enhancing the collaboration and coordination among the Research Projects and Scientific Cores. In order to elucidate the mechanisms of CAM therapies and optimize treatments, the Research Projects rely on an interdisciplinary approach. Furthermore, the Scientific Cores will contribute to each of the Projects as well as the Center as a whole in characterizing the patient population and advancing our mechanistic understanding of the treatments under investigation. These collaborative relationships will be fostered by the Clinical Research Core, which will link the individual components through centralized recruitment, data management and biostatistical, and regulatory resources. To advance the aims of the Center through coordinated scientific efforts, the Clinical Research Core will: 1. Manage participant recruitment, randomization, and monitoring of accrual and retention;and 2. Support interdisciplinary analyses and quality assurance through centralized data management, biostatistical expertise, and internal data monitoring;and 3. Provide oversight of regulatory requirements, participant safety, and human subjects research protections.

Public Health Relevance

The Stanford CAM Center for Chronic Back Pain aims to address the significant problem of chronic low back pain by investigating CAM therapies with a common underlying modulatory effect on pain. The Clinical Researhc Core will support the coordination necessary to understand the mechanisms behind these therapies and translate the research into optimizing the thereapeutic effect.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Research Program Projects (P01)
Project #
5P01AT006651-04
Application #
8668000
Study Section
Special Emphasis Panel (ZAT1-SM)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
4
Fiscal Year
2014
Total Cost
$62,990
Indirect Cost
$89,648
Name
Stanford University
Department
Type
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94305
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Bruehl, Stephen; Apkarian, A Vania; Ballantyne, Jane C et al. (2013) Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. J Pain 14:103-13