The Clinical Research Core will serve as a scientific resource to each of the individual components of the Stanford CAM Center for Chronic Back Pain, advancing the scientific aims fo the Center by enhancing the collaboration and coordination among the Research Projects and Scientific Cores. In order to elucidate the mechanisms of CAM therapies and optimize treatments, the Research Projects rely on an interdisciplinary approach. Furthermore, the Scientific Cores will contribute to each of the Projects as well as the Center as a whole in characterizing the patient population and advancing our mechanistic understanding of the treatments under investigation. These collaborative relationships will be fostered by the Clinical Research Core, which will link the individual components through centralized recruitment, data management and biostatistical, and regulatory resources. To advance the aims of the Center through coordinated scientific efforts, the Clinical Research Core will: 1. Manage participant recruitment, randomization, and monitoring of accrual and retention;and 2. Support interdisciplinary analyses and quality assurance through centralized data management, biostatistical expertise, and internal data monitoring;and 3. Provide oversight of regulatory requirements, participant safety, and human subjects research protections.

Public Health Relevance

The Stanford CAM Center for Chronic Back Pain aims to address the significant problem of chronic low back pain by investigating CAM therapies with a common underlying modulatory effect on pain. The Clinical Researhc Core will support the coordination necessary to understand the mechanisms behind these therapies and translate the research into optimizing the thereapeutic effect.

National Institute of Health (NIH)
National Center for Complementary & Alternative Medicine (NCCAM)
Research Program Projects (P01)
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Special Emphasis Panel (ZAT1-SM)
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Stanford University
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Sturgeon, John A; Carriere, Junie S; Kao, Ming-Chih J et al. (2016) Social Disruption Mediates the Relationship Between Perceived Injustice and Anger in Chronic Pain: a Collaborative Health Outcomes Information Registry Study. Ann Behav Med 50:802-812
Darnall, Beth D (2016) Pain Psychology and Pain Catastrophizing in the Perioperative Setting: A Review of Impacts, Interventions, and Unmet Needs. Hand Clin 32:33-9
Darnall, Beth D; Scheman, Judith; Davin, Sara et al. (2016) Pain Psychology: A Global Needs Assessment and National Call to Action. Pain Med 17:250-63
Darnall, Beth D; Schatman, Michael E (2015) The Relationship Between Industry and Pain Societies, Part 1: Demystification and Legitimization of Continuing Medical Education. Pain Med 16:1251
Darnall, Beth D; Schatman, Michael E (2015) Opioid use and lactation: protecting the child in the context of maternal pain care. Pain Med 16:628
Sturgeon, John A; Dixon, Eric A; Darnall, Beth D et al. (2015) Contributions of physical function and satisfaction with social roles to emotional distress in chronic pain: a Collaborative Health Outcomes Information Registry (CHOIR) study. Pain 156:2627-33
Darnall, Beth D (2015) ""Compassion Cultivation in Chronic Pain May Reduce Anger, Pain, and Increase Acceptance: Study Review and Brief Commentary"". Health Care Curr Rev 3:
Chapin, Heather L; Darnall, Beth D; Seppala, Emma M et al. (2014) Pilot study of a compassion meditation intervention in chronic pain. J Compassionate Health Care 1:
Darnall, Beth D (2014) Minimize opioids by optimizing pain psychology. Pain Manag 4:251-3
Darnall, Beth D; Sturgeon, John A; Kao, Ming-Chih et al. (2014) From Catastrophizing to Recovery: a pilot study of a single-session treatment for pain catastrophizing. J Pain Res 7:219-26

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