Because the Project Leaders are dispersed in various departments throughout the Medical School, the Administrative Core A plays an essential role in properly administering and maintaining the cohesion of this Program. The Core supports the effort Dr. DiMaio devotes to administering this Program and providing the scientific leadership that ensures the necessary focus and essential scientific interactions. Second, it provides support to various administrative staff to provide proper administrative services and financial management. A major service supported is secretarial assistance to prepare Continuation Reports and Renewals. Finally, it covers expenses related to visits of the External Scientific Advisory Board to Yale. Thus, Core A, which has been a component of this Program since its inception, is essential for it to function as an efficient, cohesive unit.
This is an interdepartmental, multi-investigator grant comprised of five projects designed to discover new principles of the conversion of normal cells into tumor cells, and the role of viruses and mutations in this process. This Core provides administrative assistance to the Principal Investigator to ensure coordination of the projects and proper financial oversight.
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|Gorres, Kelly L; Daigle, Derek; Mohanram, Sudharshan et al. (2016) Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus. MBio 7:e00113|
|Brown, Jessica A; Kinzig, Charles G; DeGregorio, Suzanne J et al. (2016) Hoogsteen-position pyrimidines promote the stability and function of the MALAT1 RNA triple helix. RNA 22:743-9|
|Zhang, Wei; Xie, Mingyi; Shu, Mei-Di et al. (2016) A proximity-dependent assay for specific RNA-protein interactions in intact cells. RNA 22:1785-1792|
|Pawlica, Paulina; Moss, Walter N; Steitz, Joan A (2016) Host miRNA degradation by Herpesvirus saimiri small nuclear RNA requires an unstructured interacting region. RNA 22:1181-9|
|DiMaio, Daniel (2016) Thank You, Edward. Merci, Louis. PLoS Pathog 12:e1005320|
|Lee, Nara; Yario, Therese A; Gao, Jessica S et al. (2016) EBV noncoding RNA EBER2 interacts with host RNA-binding proteins to regulate viral gene expression. Proc Natl Acad Sci U S A 113:3221-6|
|Tycowski, Kazimierz T; Shu, Mei-Di; Steitz, Joan A (2016) Myriad Triple-Helix-Forming Structures in the Transposable Element RNAs of Plants and Fungi. Cell Rep 15:1266-76|
|Brown, Jessica A; Kinzig, Charles G; DeGregorio, Suzanne J et al. (2016) Methyltransferase-like protein 16 binds the 3'-terminal triple helix of MALAT1 long noncoding RNA. Proc Natl Acad Sci U S A 113:14013-14018|
|Guo, Yang Eric; Oei, Theresa; Steitz, Joan A (2015) Herpesvirus saimiri MicroRNAs Preferentially Target Host Cell Cycle Regulators. J Virol 89:10901-11|
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