Because the Project Leaders are dispersed in various departments throughout the Medical School, the Administrative Core A plays an essential role in properly administering and maintaining the cohesion of this Program. The Core supports the effort Dr. DiMaio devotes to administering this Program and providing the scientific leadership that ensures the necessary focus and essential scientific interactions. Second, it provides support to various administrative staff to provide proper administrative services and financial management. A major service supported is secretarial assistance to prepare Continuation Reports and Renewals. Finally, it covers expenses related to visits of the External Scientific Advisory Board to Yale. Thus, Core A, which has been a component of this Program since its inception, is essential for it to function as an efficient, cohesive unit.
This is an interdepartmental, multi-investigator grant comprised of five projects designed to discover new principles of the conversion of normal cells into tumor cells, and the role of viruses and mutations in this process. This Core provides administrative assistance to the Principal Investigator to ensure coordination of the projects and proper financial oversight.
|Guo, Yang Eric; Steitz, Joan A (2014) 3'-Biotin-tagged microRNA-27 does not associate with Argonaute proteins in cells. RNA 20:985-8|
|Goodwin, Edward C; Motamedi, Nasim; Lipovsky, Alex et al. (2014) Expression of DNAJB12 or DNAJB14 causes coordinate invasion of the nucleus by membranes associated with a novel nuclear pore structure. PLoS One 9:e94322|
|Cech, Thomas R; Steitz, Joan A (2014) The noncoding RNA revolution-trashing old rules to forge new ones. Cell 157:77-94|
|Dimaio, Daniel (2014) Is virology dead? MBio 5:e01003-14|
|Guo, Yang Eric; Riley, Kasandra J; Iwasaki, Akiko et al. (2014) Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function. Mol Cell 54:67-79|
|Carney, Daniel W; Nelson, Christian D S; Ferris, Bennett D et al. (2014) Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem 22:4836-47|
|Zhang, Wei; Kazakov, Teymur; Popa, Andreea et al. (2014) Vesicular trafficking of incoming human papillomavirus 16 to the Golgi apparatus and endoplasmic reticulum requires ?-secretase activity. MBio 5:e01777-14|
|Xie, Mingyi; Steitz, Joan A (2014) Versatile microRNA biogenesis in animals and their viruses. RNA Biol 11:673-81|
|Park, Richard; El-Guindy, Ayman; Heston, Lee et al. (2014) Nuclear translocation and regulation of intranuclear distribution of cytoplasmic poly(A)-binding protein are distinct processes mediated by two Epstein Barr virus proteins. PLoS One 9:e92593|
|Guo, Yang Eric; Steitz, Joan A (2014) Virus meets host microRNA: the destroyer, the booster, the hijacker. Mol Cell Biol 34:3780-7|
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