The Administration/Statistics (Admin/Stats) core provide two essential elements: oversight of the program project grant and expertise in statistics and bioinformatics. Oversight occurs at multiple levels, intellectual, administrative and financial. Intellectual oversight is achieved through multiple levels of interactions by the PI with Project leaders and their lab members, and with Core leaders. An external scientific board provides annual assessments of the program and advises Dr. Lambert of its findings. Administrative oversight is provided by Ms. Bette Sheehan, who has served this role for neariy 30 years helping to facilitate the multiple mechanisms of interaction as well as coordinating the training efforts of the members of each lab. Financial oversight is provided by Randy Martinson, who coordinates the management ofthe grant ensuring that monies are allocated appropriately and used efficiently to support the projects'and cores'needs. Ms. Sheehan and Mr Martinson report directly to Dr. Lambert. New to this competitive renewal is a statistics/bioinformatics section of this core that is led by Drs. Norman Drinkwater and Michael Newton. They will provide expertise in statistical analysis of animal/lab experiments as well as genome-wide analyses. Drs. Drinkwater and Newton have been supported during this current funding period on individual projects. We have transitioned to placing their expertise in the context of this core because their expertise is required now across all five projects. Dr. Lambert will oversee the successful integration of this new core activity into the PPG.

Public Health Relevance

Human viruses cause a multitude of human cancers. Understanding the biology of these viruses and their role in these cancers is essential for learning how to eradicate these cancers. This administrative core provides oversight over this program project grant at multiple levels as well as expertise in statistics and bioinformatics

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA022443-36
Application #
8512987
Study Section
Special Emphasis Panel (ZCA1-RPRB-2 (J1))
Project Start
Project End
Budget Start
2013-05-01
Budget End
2014-04-30
Support Year
36
Fiscal Year
2013
Total Cost
$120,369
Indirect Cost
$40,390
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Weng, Chao; Lee, Denis; Gelbmann, Christopher B et al. (2018) Human Cytomegalovirus Productively Replicates In Vitro in Undifferentiated Oral Epithelial Cells. J Virol 92:
Bristol, Jillian A; Djavadian, Reza; Albright, Emily R et al. (2018) A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection. PLoS Pathog 14:e1007179
Romero-Masters, James C; Ohashi, Makoto; Djavadian, Reza et al. (2018) An EBNA3C-deleted Epstein-Barr virus (EBV) mutant causes B-cell lymphomas with delayed onset in a cord blood-humanized mouse model. PLoS Pathog 14:e1007221
UmaƱa, Angie C; Iwahori, Satoko; Kalejta, Robert F (2018) Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk). ACS Chem Biol 13:189-199
Meyers, Jordan M; Grace, Miranda; Uberoi, Aayushi et al. (2018) Inhibition of TGF-? and NOTCH Signaling by Cutaneous Papillomaviruses. Front Microbiol 9:389
Uberoi, Aayushi; Yoshida, Satoshi; Lambert, Paul F (2018) Development of an in vivo infection model to study Mouse papillomavirus-1 (MmuPV1). J Virol Methods 253:11-17
Djavadian, Reza; Hayes, Mitchell; Johannsen, Eric (2018) CAGE-seq analysis of Epstein-Barr virus lytic gene transcription: 3 kinetic classes from 2 mechanisms. PLoS Pathog 14:e1007114
Chakravorty, Adityarup; Sugden, Bill (2018) Long-distance communication: Looping of human papillomavirus genomes regulates expression of viral oncogenes. PLoS Biol 16:e3000062
Chiu, Ya-Fang; Sugden, Bill (2018) Plasmid Partitioning by Human Tumor Viruses. J Virol 92:
Shin, Myeong-Kyun; Payne, Susan N; Bilger, Andrea et al. (2018) Activating Mutations in Pik3caContribute to Anal Carcinogenesis in the Presence or Absence of HPV-16 Oncogenes. Clin Cancer Res :

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