C o r e C The Administrative Core (Core C) provides leadership and administrative support for the planning, coordination, implementation and ongoing review of the individual research projects, cores and program of clinical trials to be conducted under the proposed Program Project. To foster the scientific and clinical objectives ofthe individual projeds and the Program Project as a whole, this core conducts periodic meetings with the participating principal investigators to develop strategic plans and consensual decisions regarding program development and organizes periodic reviews of research progress and productivity by external scientific advisory committees. This Core also provides direction and coordination for the activities of the transplant program's integrated data management. The core also maintains and facilitates communication between investigators in the individual projects and cores through weekly conferences and research-in-progress presentations. Lastly, this Core provides fiscal management services for the projects and cores of the Program Project, and provides critical analytic support for the preparation of research progress reports and interim analyses of clinical trials as required by the IRB, NMDP, NIH and, as applicable the FDA.

Public Health Relevance

This Administrative Core provides scientific leadership and overall direction to the Program. This ensures appropriately frugal use of limited resources for maximal effect. This core also has and will continue to foster rapid translation of discoveries made in the Research Project into clinical trials and ultimate extension to the community.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA023766-34
Application #
8435577
Study Section
Special Emphasis Panel (ZCA1-RPRB-B (O1))
Project Start
1998-09-01
Project End
2018-03-31
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
34
Fiscal Year
2013
Total Cost
$188,390
Indirect Cost
$81,834
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
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Fischer, Julius C; Bscheider, Michael; Eisenkolb, Gabriel et al. (2017) RIG-I/MAVS and STING signaling promote gut integrity during irradiation- and immune-mediated tissue injury. Sci Transl Med 9:
Goldberg, Jenna D; Zheng, Junting; Ratan, Ravin et al. (2017) Early recovery of T-cell function predicts improved survival after T-cell depleted allogeneic transplant. Leuk Lymphoma 58:1859-1871
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