The Specific Aims of the Animal Core are: 1. To serve as a regional referral center for dogs with spontaneous tumors that will be treated on projects in this program. 2. To provide the necessary diagnostic and staging services to assess whether animal patients are suitable for treatment in the program. 3. To provide personnel resources for administration of treatments used in dogs with spontaneous tumors treated in this program. 4. To provide personnel resources for follow-up of dogs with spontaneous tumors treated in this program. 5. To provide quality assurance for standardization of treatments for projects in this program in which dogs with spontaneous tumors are treated. 6. To provide data accrual and archiving support regarding information collected from dogs treated on projects in this program.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA042745-10
Application #
5207343
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Stauffer, Paul R; van Rhoon, Gerard C (2016) Overview of bladder heating technology: matching capabilities with clinical requirements. Int J Hyperthermia 32:407-16
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Inman, Brant A; Stauffer, Paul R; Craciunescu, Oana A et al. (2014) A pilot clinical trial of intravesical mitomycin-C and external deep pelvic hyperthermia for non-muscle-invasive bladder cancer. Int J Hyperthermia 30:171-5
Angele, Martin K; Albertsmeier, Markus; Prix, Niclas J et al. (2014) Effectiveness of regional hyperthermia with chemotherapy for high-risk retroperitoneal and abdominal soft-tissue sarcoma after complete surgical resection: a subgroup analysis of a randomized phase-III multicenter study. Ann Surg 260:749-54; discussion 754-6
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Viglianti, Benjamin L; Dewhirst, Mark W; Boruta, R J et al. (2014) Systemic anti-tumour effects of local thermally sensitive liposome therapy. Int J Hyperthermia 30:385-92
Dewhirst, Mark W; Chi, Jen-Tsan (2013) Understanding the tumor microenvironment and radioresistance by combining functional imaging with global gene expression. Semin Radiat Oncol 23:296-305
Paulides, Margarethus M; Stauffer, Paul R; Neufeld, Esra et al. (2013) Simulation techniques in hyperthermia treatment planning. Int J Hyperthermia 29:346-57
Cao, Yiting; Eble, Joseph M; Moon, Ejung et al. (2013) Tumor cells upregulate normoxic HIF-1? in response to doxorubicin. Cancer Res 73:6230-42
Boss, M Keara; Muradyan, N; Thrall, D E (2013) DCE-MRI: a review and applications in veterinary oncology. Vet Comp Oncol 11:87-100

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