The Biostatistics and Data Management Core provides the statistical and data management support required for individual projects in order to achieve the goals of the Program Project as a whole. Statistical support includes the following activities: 1) full collaboration with laboratory and clinical investigators to ensure that both laboratory and clinical studies are well designed both statistically and scientifically;2) monitoring of ongoing laboratory studies and clinical trial providing interim analyses as necessary;3) statistical data analysis for all studies and trials conducted;4) involvement in the preparation of presentations, abstracts and manuscripts reporting on the results of all investigations. Statisticians will also be involved in data quality control. The analyst programmer will be responsible for quality-controlled data management including the creation, maintenance and validation of all databases used in laboratory and clinical studies. The programmer will also develop programs allowing electronic data transfer. The data coordinator will regularly monitor data collection and interact with both investigators and statisticians to facilitate the availability of quality data for analysis. Established teams are in place for both statistical support and data management. Computer and data systems are operational for fulfilling the missions described above.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA047741-20
Application #
8539269
Study Section
Special Emphasis Panel (ZCA1-RPRB-J)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
20
Fiscal Year
2013
Total Cost
$122,762
Indirect Cost
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Rowland, Christopher R; Colucci, Lina A; Guilak, Farshid (2016) Fabrication of anatomically-shaped cartilage constructs using decellularized cartilage-derived matrix scaffolds. Biomaterials 91:57-72
Flynn, Ryan; Paz, Katelyn; Du, Jing et al. (2016) Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism. Blood 127:2144-54
Brennan, Todd V; Lin, Liwen; Brandstadter, Joshua D et al. (2016) Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation. J Clin Invest 126:207-19
Sung, Anthony D; Sung, Julia A M; Thomas, Samantha et al. (2016) Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial. Clin Infect Dis 63:999-1006
Brennan, Todd V; Rendell, Victoria R; Yang, Yiping (2015) Innate immune activation by tissue injury and cell death in the setting of hematopoietic stem cell transplantation. Front Immunol 6:101
Tuchman, Sascha A; Bacon, Wendi A; Huang, Li-Wen et al. (2015) Cyclophosphamide-based hematopoietic stem cell mobilization before autologous stem cell transplantation in newly diagnosed multiple myeloma. J Clin Apher 30:176-82
Brandstadter, Joshua D; Huang, Xiaopei; Yang, Yiping (2014) NK cell-extrinsic IL-18 signaling is required for efficient NK-cell activation by vaccinia virus. Eur J Immunol 44:2659-66
Horwitz, Mitchell E; Chao, Nelson J; Rizzieri, David A et al. (2014) Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment. J Clin Invest 124:3121-8
Brunger, Jonathan M; Huynh, Nguyen P T; Guenther, Caitlin M et al. (2014) Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. Proc Natl Acad Sci U S A 111:E798-806
Macintyre, Andrew N; Gerriets, Valerie A; Nichols, Amanda G et al. (2014) The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. Cell Metab 20:61-72

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