Public Health Relevance

This Core serves a key function in leading and coordinating this highly translational Program Project Grant toward a better understanding of mechanisms and effects of photodynamic therapy and its clinical application in the treatment of malignant disease.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA055791-20
Application #
8462221
Study Section
Special Emphasis Panel (ZCA1-GRB-P)
Project Start
Project End
2015-01-31
Budget Start
2013-02-01
Budget End
2014-01-31
Support Year
20
Fiscal Year
2013
Total Cost
$143,997
Indirect Cost
$57,905
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
824771034
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Baran, Timothy M; Foster, Thomas H (2014) Comparison of flat cleaved and cylindrical diffusing fibers as treatment sources for interstitial photodynamic therapy. Med Phys 41:022701
Lai, Jinhuo; Cai, Qian; Biel, Merrill A et al. (2014) Id1 and NF-?B promote the generation of CD133+ and BMI-1+ keratinocytes and the growth of xenograft tumors in mice. Int J Oncol 44:1481-9
Rohrbach, Daniel J; Muffoletto, Daniel; Huihui, Jonathan et al. (2014) Preoperative mapping of nonmelanoma skin cancer using spatial frequency domain and ultrasound imaging. Acad Radiol 21:263-70
Rigual, Nestor; Shafirstein, Gal; Cooper, Michele T et al. (2013) Photodynamic therapy with 3-(1'-hexyloxyethyl) pyropheophorbide a for cancer of the oral cavity. Clin Cancer Res 19:6605-13
James, Nadine S; Chen, Yihui; Joshi, Penny et al. (2013) Evaluation of polymethine dyes as potential probes for near infrared fluorescence imaging of tumors: part - 1. Theranostics 3:692-702
Zeitouni, Nathalie C; Paquette, Anne D; Housel, Joseph P et al. (2013) A retrospective review of pain control by a two-step irradiance schedule during topical ALA-photodynamic therapy of non-melanoma skin cancer. Lasers Surg Med 45:89-94
Mitra, Soumya; Modi, Kshitij D; Foster, Thomas H (2013) Enzyme-activatable imaging probe reveals enhanced neutrophil elastase activity in tumors following photodynamic therapy. J Biomed Opt 18:101314
Ethirajan, Manivannan; Chen, Ping; Ohulchanskyy, Tymish Y et al. (2013) Regioselective synthesis and photophysical and electrochemical studies of 20-substituted cyanine dye-purpurinimide conjugates: incorporation of Ni(II) into the conjugate enhances its tumor-uptake and fluorescence-imaging ability. Chemistry 19:6670-84
Rigual, Nestor R; Shafirstein, Gal; Frustino, Jennifer et al. (2013) Adjuvant intraoperative photodynamic therapy in head and neck cancer. JAMA Otolaryngol Head Neck Surg 139:706-11
Brackett, Craig M; Muhitch, Jason B; Evans, Sharon S et al. (2013) IL-17 promotes neutrophil entry into tumor-draining lymph nodes following induction of sterile inflammation. J Immunol 191:4348-57

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