The Administrative Core A consists of a highly qualified group of scientific and administrative experts assembled to maintain the focus and progress of the Program Project. This highly experienced core leadership facilitates synergistic exchange between all projects and cores. Dr. Raymond N. DuBois, serves as Principal Investigator and has the primary responsibility for all aspects of the Program. He is assisted by an exceptional group of Project Leaders and Core Directors, Scientific Advisory Board participants, administrative personnel and biostatistical staff. The Core A administrative personnel will manage annual budgets, monitor expenses, and provide timely statements of financial activities. Biostatistics, bioinformatics, computational biology, quantitative analyses and interpretation of data will be made accessible to all Program Project participants through the most appropriate experts in the Division of Quantitative Sciences at UTMDACC. This core will assume full responsibility for planning, scheduling and sponsoring all Program Project connected meetings. These meetings include quarterly steering committee meetings and videoconferences. Project and Core Leaders will routinely meet to evaluate productivity, allocate core resources and usage in addition to developing strategies and directions for future program efforts. Routine scientific videoconferences will enable investigators to share current findings, identify problems, and implement solutions. Scientific Advisory Board Meetings will be held in the first and fourth years of the Project. All review materials and evaluation procedures will be handled through Core A. Furthermore, Core A will organize and coordinate two scientific retreats per annum. Core A will prepare, collate and assemble data as well as materials necessary for annual progress reports. The oversight of any NIH and institutional reporting and compliance measures will be coordinated through Core A to fulfill all Program Project obligations in a timely fashion.

Public Health Relevance

The Administrative Core A consists of highly experienced core leadership that has facilitated the synergistic exchange between all projects and cores throughout the their tenure. Dr. DuBois is assisted by an exceptional group of Project Leaders and Core Directors, Scientific Advisory Board participants, administrative personnel and biostatistical staff, which has also been effectively transitioned from VU to UTMDACC.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA077839-13
Application #
8677713
Study Section
Special Emphasis Panel (ZCA1-RPRB-O)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
13
Fiscal Year
2014
Total Cost
$108,239
Indirect Cost
$24,803
Name
Mayo Clinic, Arizona
Department
Type
DUNS #
153665211
City
Scottsdale
State
AZ
Country
United States
Zip Code
85259
Sun, Xiaofei; Park, Craig B; Deng, Wenbo et al. (2016) Uterine inactivation of muscle segment homeobox (Msx) genes alters epithelial cell junction proteins during embryo implantation. FASEB J 30:1425-35
Wang, Dingzhi; DuBois, Raymond N (2016) The Role of Prostaglandin E(2) in Tumor-Associated Immunosuppression. Trends Mol Med 22:1-3
Hiraoka, Takehiro; Hirota, Yasushi; Saito-Fujita, Tomoko et al. (2016) STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation. JCI Insight 1:
Yuan, Jia; Cha, Jeeyeon; Deng, Wenbo et al. (2016) Planar cell polarity signaling in the uterus directs appropriate positioning of the crypt for embryo implantation. Proc Natl Acad Sci U S A 113:E8079-E8088
Reddy, Vishruth K; Short, Sarah P; Barrett, Caitlyn W et al. (2016) BVES Regulates Intestinal Stem Cell Programs and Intestinal Crypt Viability after Radiation. Stem Cells 34:1626-36
Sones, Jenny L; Cha, Jeeyeon; Woods, Ashley K et al. (2016) Decidual Cox2 inhibition improves fetal and maternal outcomes in a preeclampsia-like mouse model. JCI Insight 1:
Etemadi, Nima; Chopin, Michael; Anderton, Holly et al. (2015) TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1. Elife 4:
Proia, Richard L; Hla, Timothy (2015) Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy. J Clin Invest 125:1379-87
Li, Mei-Hong; Swenson, Rolf; Harel, Miriam et al. (2015) Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma. J Pharmacol Exp Ther 354:261-8
Wang, Dingzhi; Fu, Lingchen; Sun, Haiyan et al. (2015) Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice. Gastroenterology 149:1884-1895.e4

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