Core A is responsible for cohort follow-up and database maintenance in the Nurses'Health Study.
The specific aims for this core are as follows: 1) Develop and mail biennial follow-up questionnaires to cohort participants 2) Process returned questionnaires and verify responses 3) Compile databases of exposure data 4) Trace lost participants and maintain an updated name and address file 5) Sustain high cohort participation Under the direction of Diane Feskanich, ScD, Core A develops and designs the questionnaire for biennial follow-up of study participants. Questionnaire design incorporates input from all investigators on the Program Project, as well as other collaborating investigators, through bi-weekly meetings. New questions are pilot tested and follow-up methods are refined to address the needs of the cohort members. Returned questionnaires are checked for completeness, optically scanned, and verified for errors. Over 80,000 questionnaires are returned in every follow-up cycle. Core A uses a range of methods to trace participants and to maintain a high 90% response rate. Returned questionnaires are digitally imaged and stored on DVD, from which they are easily retrievable. Exposure data from the questionnaires are complied into databases and variables are derived and documented for use by investigators. This includes maintenance of nutrient intakes derived from the food frequency portion of the questionnaire. Diseases reported on the questionnaires are passed to Core B for confirmation.

Public Health Relevance

Core A activities are critical for gathering exposure and disease information and for maintaining follow-up in the Nurses'Health Study and hence for maintaining the validity of all analyses conducted in Projects 1-4. By extension, this Core is vital to our ability to find ways to prevent cancer Incidence and improve survival in women.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA087969-14
Application #
8513147
Study Section
Special Emphasis Panel (ZCA1-RPRB-7)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
14
Fiscal Year
2013
Total Cost
$594,616
Indirect Cost
$112,600
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Chiu, Yu-Han; Bertrand, Kimberly A; Zhang, Shumin et al. (2018) A prospective analysis of circulating saturated and monounsaturated fatty acids and risk of non-Hodgkin lymphoma. Int J Cancer 143:1914-1922
Petrick, Jessica L; Campbell, Peter T; Koshiol, Jill et al. (2018) Tobacco, alcohol use and risk of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: The Liver Cancer Pooling Project. Br J Cancer 118:1005-1012
He, Xiaosheng; Wu, Kana; Ogino, Shuji et al. (2018) Association Between Risk Factors for Colorectal Cancer and Risk of Serrated Polyps and Conventional Adenomas. Gastroenterology 155:355-373.e18
Wang, Sophia S; Carrington, Mary; Berndt, Sonja I et al. (2018) HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes. Cancer Res 78:4086-4096
Kim, Hanseul; Keum, NaNa; Giovannucci, Edward L et al. (2018) Garlic intake and gastric cancer risk: Results from two large prospective US cohort studies. Int J Cancer 143:1047-1053
Liu, Li; Tabung, Fred K; Zhang, Xuehong et al. (2018) Diets That Promote Colon Inflammation Associate With Risk of Colorectal Carcinomas That Contain Fusobacterium nucleatum. Clin Gastroenterol Hepatol 16:1622-1631.e3
Lin, Brian M; Li, Wen-Qing; Cho, Eunyoung et al. (2018) Statin use and risk of skin cancer. J Am Acad Dermatol 78:682-693
AlDubayan, Saud H; Giannakis, Marios; Moore, Nathanael D et al. (2018) Inherited DNA-Repair Defects in Colorectal Cancer. Am J Hum Genet 102:401-414
Li, Wen-Qing; Drucker, Aaron M; Cho, Eunyoung et al. (2018) Tetracycline use and risk of incident skin cancer: a prospective study. Br J Cancer 118:294-298
Bailey, Jessica N Cooke; Gharahkhani, Puya; Kang, Jae H et al. (2018) Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets. Invest Ophthalmol Vis Sci 59:629-636

Showing the most recent 10 out of 1708 publications