The Morphology Core (Core B) has the following responsibilities: 1. Provide the Pis and other investigators of the four projects with expert advice in the selection and application of optimal morphological techniques to address specific questions and problems in their research. 2. Perform advanced morphological applications that will include in situ hybridization, confocal laser scanning microscopy, plastic one micron section light microscopy, transmission electron microscopy, electron microscopic immuno(gold)cytochemistry, and laser capture microdissection. 3. Provide expertise in interpreting results obtained with the various morphological techniques. 4. Allocate the equipment, personnel and other resources fairly and to the optimal performance of the program project'

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA092644-10
Application #
8459038
Study Section
Special Emphasis Panel (ZCA1-GRB-S)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
10
Fiscal Year
2013
Total Cost
$134,970
Indirect Cost
$43,073
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215
Gross, Kayla; Wronski, Ania; Skibinski, Adam et al. (2016) Cell Fate Decisions During Breast Cancer Development. J Dev Biol 4:4
Sedic, Maja; Kuperwasser, Charlotte (2016) BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancer. Cell Cycle 15:621-7
Dvorak, Harold F (2015) Tumors: wounds that do not heal-redux. Cancer Immunol Res 3:1-11
Dvorak, Harold F (2015) Tumor Stroma, Tumor Blood Vessels, and Antiangiogenesis Therapy. Cancer J 21:237-43
Mazumdar, Sohini; Arendt, Lisa M; Phillips, Sarah et al. (2015) CoREST1 promotes tumor formation and tumor stroma interactions in a mouse model of breast cancer. PLoS One 10:e0121281
Sedic, Maja; Skibinski, Adam; Brown, Nelson et al. (2015) Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nat Commun 6:7505
Sciuto, Tracey E; Merley, Anne; Lin, Chi-Iou et al. (2015) Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells. Biochem Biophys Res Commun 465:338-43
Kaunisto, Aura; Henry, Whitney S; Montaser-Kouhsari, Laleh et al. (2015) NFAT1 promotes intratumoral neutrophil infiltration by regulating IL8 expression in breast cancer. Mol Oncol 9:1140-54
Rowe, Glenn C; Raghuram, Srilatha; Jang, Cholsoon et al. (2014) PGC-1α induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle. Circ Res 115:504-17
Skibinski, Adam; Breindel, Jerrica L; Prat, Aleix et al. (2014) The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment. Cell Rep 6:1059-72

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