The Morphology Core (Core B) has the following responsibilities: 1. Provide the Pis and other investigators of the four projects with expert advice in the selection and application of optimal morphological techniques to address specific questions and problems in their research. 2. Perform advanced morphological applications that will include in situ hybridization, confocal laser scanning microscopy, plastic one micron section light microscopy, transmission electron microscopy, electron microscopic immuno(gold)cytochemistry, and laser capture microdissection. 3. Provide expertise in interpreting results obtained with the various morphological techniques. 4. Allocate the equipment, personnel and other resources fairly and to the optimal performance of the program project'

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1-GRB-S)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Beth Israel Deaconess Medical Center
United States
Zip Code
Skibinski, Adam; Breindel, Jerrica L; Prat, Aleix et al. (2014) The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment. Cell Rep 6:1059-72
Lin, Chi-Iou; Merley, Anne; Sciuto, Tracey E et al. (2014) TM4SF1: a new vascular therapeutic target in cancer. Angiogenesis 17:897-907
Chin, Y Rebecca; Yoshida, Taku; Marusyk, Andriy et al. (2014) Targeting Akt3 signaling in triple-negative breast cancer. Cancer Res 74:964-73
Chin, Y Rebecca; Yuan, Xin; Balk, Steven P et al. (2014) PTEN-deficient tumors depend on AKT2 for maintenance and survival. Cancer Discov 4:942-55
Phillips, Sarah; Prat, Aleix; Sedic, Maja et al. (2014) Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation. Stem Cell Reports 2:633-47
Lin, Chi-Iou; Lau, Chun-Yee; Li, Dan et al. (2014) Nanopodia--thin, fragile membrane projections with roles in cell movement and intercellular interactions. J Vis Exp :
Rowe, Glenn C; Raghuram, Srilatha; Jang, Cholsoon et al. (2014) PGC-1? induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle. Circ Res 115:504-17
Elloul, Sivan; Kedrin, Dmitriy; Knoblauch, Nicholas W et al. (2014) The adherens junction protein afadin is an AKT substrate that regulates breast cancer cell migration. Mol Cancer Res 12:464-76
Kazerounian, Shiva; Gerald, Damien; Huang, Minzhou et al. (2013) RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesis. Cancer Res 73:50-61
Arendt, Lisa M; McCready, Jessica; Keller, Patricia J et al. (2013) Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis. Cancer Res 73:6080-93

Showing the most recent 10 out of 100 publications