The Administrative Core will provide critical centralized grant administration, data processing, and administrative support for the projects and cores. This Core will also serve to amalgamate the investigators, their experimental findings and their ideas, evaluation of research efforts and critically direct the summary efforts toward maintaining a highly integrated program outcome. It functions to: 1). Provide administrative services to the investigators. This includes the management of project supplies, filing, development of memos, meeting minutes and communications covering all operations, including publications;2) Organize monthly or bi-monthly meetings/conferences of program project personnel;quarterly meetings of the Program Steering Committee;3). Organize semiannual meetings of the Internal Advisory Board and annual meetings of the External Advisory Board. 4). Maintain integration activities that include data sharing, rapid publication efforts, and identify and institute other novel activities critical to maintaining and strengthening the integration of the program. 5). Provide overall fiscal review, accounting, and real time budgets analyses. This includes reports, verbal communications, reviews and forward-looking projections on expenditures. This core is essential for the program integration and effective communication of the scientific program.

Public Health Relevance

The Administrative Core is essential for the functions of the Program Project for discovering the role of tumor microenvironment in the breast tumorigenesis and for translating these discoveries into innovative approaches for the diagnosis and treatment of breast cancer.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
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Special Emphasis Panel (ZCA1-RPRB-O)
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Ohio State University
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Mathsyaraja, H; Thies, K; Taffany, D A et al. (2015) CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. Oncogene 34:3651-61
Meisen, Walter Hans; Dubin, Samuel; Sizemore, Steven T et al. (2015) Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies. Mol Cancer Ther 14:307-14
Kabbout, Mohamed; Dakhlallah, Duaa; Sharma, Sudarshana et al. (2014) MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation. PLoS One 9:e100693
Wallace, Julie A; Li, Fu; Balakrishnan, Subhasree et al. (2013) Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer. PLoS One 8:e71533
Bronisz, A; Godlewski, J; Wallace, J A et al. (2012) Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320. Nat Cell Biol 14:159-67
Ouseph, Madhu M; Li, Jing; Chen, Hui-Zi et al. (2012) Atypical E2F repressors and activators coordinate placental development. Dev Cell 22:849-62
Thudi, Nanda K; Martin, Chelsea K; Murahari, Sridhar et al. (2011) Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases. Prostate 71:615-25
Wenzel, Pamela L; Chong, Jean-Leon; Saenz-Robles, M Teresa et al. (2011) Cell proliferation in the absence of E2F1-3. Dev Biol 351:35-45
Wallace, Julie A; Li, Fu; Leone, Gustavo et al. (2011) Pten in the breast tumor microenvironment: modeling tumor-stroma coevolution. Cancer Res 71:1203-7
Trikha, Prashant; Sharma, Nidhi; Opavsky, Rene et al. (2011) E2f1-3 are critical for myeloid development. J Biol Chem 286:4783-95

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