Young adulthood is the developmental period when cigarette smoking becomes more entrenched, with dramatic increases in intensity occurring after age 18 (Hammond, 2005). In order for us to continue to make gains in reducing rates of cigarette smoking, we need to address the problem of smoking among young adults. This project will use Ecological Momentary Assessments (EMA) to gather real-time, naturalistic self reports of young adults'daily experiences and smoking behavior to examine how the immediate situation (proximal context) in which smoking occurs, along with the individual's subjective reactions to those experiences, varies by smoking level and influences future smoking behavior. This proposed project builds on several of our compelling findings to date with our current program project. These findings include: a) Mood just prior to smoking differs significantly from random, background times, such that when adolescents smoke, they feel less positive and more negative than other times. b) Following smoking, adolescents experience a significant relief of negative affect and boost in positive affect, c) Importantly, this change in affect predicts smoking trajectory - adolescents who belong to the trajectory with the lowest level of use and who do not escalate in their smoking derived the least amount of positive affective change following smoking;that is, these youth did not experience the """"""""boost"""""""" following smoking, d) Mood variability, and not just overall level of mood, may be important in predicting escalation. e) Adolescents experience subjective aspects of withdrawal and dependence, even at relatively low levels of smoking. And f) Conjoint alcohol use and smoking may diminish the subjective mood boosts from smoking, although social context may be an important moderator. As we follow participants into young adulthood and as their smoking progresses, we will focus specifically on affective prompts and consequences to smoking, tracking of withdrawal symptoms, including new measures of attention, craving, as well as satisfaction with smoking, and the influence of alcohol and social contexts on smoking. This proposed project presents a unique opportunity to track and examine the development of dependence from adolescence through young adulthood. Thus, this project is well positioned to make a unique contribution to our understanding of the development of smoking patterns and nicotine dependence.

Public Health Relevance

In order for us to continue to make gains in reducing rates of cigarette smoking, we need to address the problem of smoking among young adults, the age group with the highest rates of smoking. This project will use Ecological Momentary Assessments (EMA) to gather real-time, naturalistic self-reports of young adults daily experiences and smoking behavior to examine how the immediate situation (proximal context) in which smoking occurs, along with the individual's subjective reactions to those experiences, varies by smoking level and influences future smoking behavior. This project presents a unique opportunity to track and examine the development of dependence from adolescence through young adulthood, and as such, should help in developing future interventions.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA098262-09
Application #
8546688
Study Section
Special Emphasis Panel (ZCA1-RPRB-7)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
9
Fiscal Year
2013
Total Cost
$98,604
Indirect Cost
Name
University of Illinois at Chicago
Department
Type
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612
Cannon, Dale S; Mermelstein, Robin J; Medina, Tait R et al. (2016) CYP2A6 Effects on Subjective Reactions to Initial Smoking Attempt. Nicotine Tob Res 18:637-41
Dierker, Lisa; Selya, Arielle; Rose, Jennifer et al. (2016) Nicotine Dependence and Alcohol Problems from Adolescence to Young Adulthood. Dual Diagn (Foster City) 1:
Crane, Natania A; Gorka, Stephanie M; Giedgowd, Grace E et al. (2016) Adolescent's respiratory sinus arrhythmia is associated with smoking rate five years later. Biol Psychol 118:107-13
Pugach, Oksana; Cannon, Dale S; Weiss, Robert B et al. (2016) Classification Tree Analysis as a Method for Uncovering Relations Between CHRNA5A3B4 and CHRNB3A6 in Predicting Smoking Progression in Adolescent Smokers. Nicotine Tob Res :
Hertel, Andrew W; Mermelstein, Robin J (2016) Smoker identity development among adolescents who smoke. Psychol Addict Behav 30:475-83
Piasecki, Thomas M; Hedeker, Donald; Dierker, Lisa C et al. (2016) Progression of nicotine dependence, mood level, and mood variability in adolescent smokers. Psychol Addict Behav 30:484-93
Cannon, Dale S; Medina, Tait R; Mermelstein, Robin J et al. (2016) CYP2A6 Longitudinal Effects in Young Smokers. Nicotine Tob Res 18:196-203
Hedeker, Donald; Mermelstein, Robin J; Demirtas, Hakan et al. (2016) A Mixed-effects Location-Scale Model for Ordinal Questionnaire Data. Health Serv Outcomes Res Methodol 16:117-131
Gao, Weihua; Hedeker, Donald; Mermelstein, Robin et al. (2016) A scalable approach to measuring the impact of nonignorable nonresponse with an EMA application. Stat Med 35:5579-5602
Schuster, Randi Melissa; Mermelstein, Robin J; Hedeker, Donald (2016) Ecological momentary assessment of working memory under conditions of simultaneous marijuana and tobacco use. Addiction 111:1466-76

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