Young adulthood is the developmental period when cigarette smoking becomes more entrenched, with dramatic increases in intensity occurring after age 18 (Hammond, 2005). In order for us to continue to make gains in reducing rates of cigarette smoking, we need to address the problem of smoking among young adults. This project will use Ecological Momentary Assessments (EMA) to gather real-time, naturalistic self reports of young adults'daily experiences and smoking behavior to examine how the immediate situation (proximal context) in which smoking occurs, along with the individual's subjective reactions to those experiences, varies by smoking level and influences future smoking behavior. This proposed project builds on several of our compelling findings to date with our current program project. These findings include: a) Mood just prior to smoking differs significantly from random, background times, such that when adolescents smoke, they feel less positive and more negative than other times. b) Following smoking, adolescents experience a significant relief of negative affect and boost in positive affect, c) Importantly, this change in affect predicts smoking trajectory - adolescents who belong to the trajectory with the lowest level of use and who do not escalate in their smoking derived the least amount of positive affective change following smoking;that is, these youth did not experience the "boost" following smoking, d) Mood variability, and not just overall level of mood, may be important in predicting escalation. e) Adolescents experience subjective aspects of withdrawal and dependence, even at relatively low levels of smoking. And f) Conjoint alcohol use and smoking may diminish the subjective mood boosts from smoking, although social context may be an important moderator. As we follow participants into young adulthood and as their smoking progresses, we will focus specifically on affective prompts and consequences to smoking, tracking of withdrawal symptoms, including new measures of attention, craving, as well as satisfaction with smoking, and the influence of alcohol and social contexts on smoking. This proposed project presents a unique opportunity to track and examine the development of dependence from adolescence through young adulthood. Thus, this project is well positioned to make a unique contribution to our understanding of the development of smoking patterns and nicotine dependence.

Public Health Relevance

In order for us to continue to make gains in reducing rates of cigarette smoking, we need to address the problem of smoking among young adults, the age group with the highest rates of smoking. This project will use Ecological Momentary Assessments (EMA) to gather real-time, naturalistic self-reports of young adults daily experiences and smoking behavior to examine how the immediate situation (proximal context) in which smoking occurs, along with the individual's subjective reactions to those experiences, varies by smoking level and influences future smoking behavior. This project presents a unique opportunity to track and examine the development of dependence from adolescence through young adulthood, and as such, should help in developing future interventions.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA098262-10
Application #
8734232
Study Section
Special Emphasis Panel (ZCA1-RPRB-7)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
10
Fiscal Year
2014
Total Cost
$171,688
Indirect Cost
$73,275
Name
University of Illinois at Chicago
Department
Type
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612
Dierker, Lisa; Rose, Jennifer; Selya, Arielle et al. (2015) Depression and nicotine dependence from adolescence to young adulthood. Addict Behav 41:124-8
Nadell, Melanie J; Mermelstein, Robin J; Hedeker, Donald et al. (2015) Work and Non-Work Physical Activity Predict Real-Time Smoking Level and Urges in Young Adults. Nicotine Tob Res 17:803-9
Hedeker, Donald (2015) Methods for Multilevel Ordinal Data in Prevention Research. Prev Sci 16:997-1006
Coon, Hilary; Piasecki, Thomas M; Cook, Edwin H et al. (2014) Association of the CHRNA4 neuronal nicotinic receptor subunit gene with frequency of binge drinking in young adults. Alcohol Clin Exp Res 38:930-7
Pugach, Oksana; Hedeker, Donald; Mermelstein, Robin (2014) A Bivariate Mixed-Effects Location-Scale Model with application to Ecological Momentary Assessment (EMA) data. Health Serv Outcomes Res Methodol 14:194-212
Pugach, Oksana; Hedeker, Donald; Richmond, Melanie J et al. (2014) Modeling mood variation and covariation among adolescent smokers: application of a bivariate location-scale mixed-effects model. Nicotine Tob Res 16 Suppl 2:S151-8
Cannon, Dale S; Mermelstein, Robin J; Hedeker, Donald et al. (2014) Effect of neuronal nicotinic acetylcholine receptor genes (CHRN) on longitudinal cigarettes per day in adolescents and young adults. Nicotine Tob Res 16:137-44
Mermelstein, Robin J (2014) Adapting to a changing tobacco landscape: research implications for understanding and reducing youth tobacco use. Am J Prev Med 47:S87-9
Piasecki, Thomas M; Trela, Constantine J; Hedeker, Donald et al. (2014) Smoking antecedents: separating between- and within-person effects of tobacco dependence in a multiwave ecological momentary assessment investigation of adolescent smoking. Nicotine Tob Res 16 Suppl 2:S119-26
Sokolovsky, Alexander W; Mermelstein, Robin J; Hedeker, Donald (2014) Factors predicting compliance to ecological momentary assessment among adolescent smokers. Nicotine Tob Res 16:351-8

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