The Participant Interaction Core serves the critical functions of centralizing communications and interactions with participants, monitoring participation rates, and serving as the public face ofthe program project. This Core will contact all participants for continued participation in the series of research studies and will maintain the cohort for the duration ofthe proposed program project. Coordinated efforts In tracking participants current contact information, assignment to specific projects, participation in these projects, and retention in the cohort is vital for the success of the proposed project. The following outline the specific aims of the Core: 1. Maintain IRB approval for the proposed project and coordinate IRB matters across all four projects and the various institutions involved in this program of research; 2. Maintain the existing cohort starting with an initial contact to inform all participants ofthe opportunity for their continued participation in the proposed project; Schedule all data collection visits with participants for each of the four projects; Collect questionnaires from Project 1 participants at four assessments (5-, 6-, 7-, &8-year followups); Collect EMA data from Project 2 participants at three major assessments (5-, 6-, &7-year follow-ups) Collect saliva samples from participants during the 5-year follow-up questionnaire visit (in Year 6) for cotinine (Project 1) and genetic (Project 4) analyses and collect additional samples as required for quality control purposes or flawed Initial samples; Track and locate participants throughout the course of the study; Coordinate the subject flow and timing of participation with special attention to the subset of participants involved in both the Project 2 ecological momentary assessment (EMA) and the Project 3 psychophysiological laboratory (LAB) studies; Coordinate data flow from this core to each project and the Data Management, Measurement, and Statistics (DMMS) Core;and Implement panel maintenance strategies across all 5 years of the longitudinal study.

Public Health Relevance

Cigarette smoking remains a significant public health problem. This program of research examines factors that influence smoking behavior during adolescence and young adulthood. This Core will provide the needed support for all of the participant Interactions required for each of the four research projects.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
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Special Emphasis Panel (ZCA1-RPRB-7)
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University of Illinois at Chicago
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Dierker, Lisa; Rose, Jennifer; Selya, Arielle et al. (2015) Depression and nicotine dependence from adolescence to young adulthood. Addict Behav 41:124-8
Nadell, Melanie J; Mermelstein, Robin J; Hedeker, Donald et al. (2015) Work and Non-Work Physical Activity Predict Real-Time Smoking Level and Urges in Young Adults. Nicotine Tob Res 17:803-9
Hedeker, Donald (2015) Methods for Multilevel Ordinal Data in Prevention Research. Prev Sci 16:997-1006
Coon, Hilary; Piasecki, Thomas M; Cook, Edwin H et al. (2014) Association of the CHRNA4 neuronal nicotinic receptor subunit gene with frequency of binge drinking in young adults. Alcohol Clin Exp Res 38:930-7
Pugach, Oksana; Hedeker, Donald; Mermelstein, Robin (2014) A Bivariate Mixed-Effects Location-Scale Model with application to Ecological Momentary Assessment (EMA) data. Health Serv Outcomes Res Methodol 14:194-212
Pugach, Oksana; Hedeker, Donald; Richmond, Melanie J et al. (2014) Modeling mood variation and covariation among adolescent smokers: application of a bivariate location-scale mixed-effects model. Nicotine Tob Res 16 Suppl 2:S151-8
Cannon, Dale S; Mermelstein, Robin J; Hedeker, Donald et al. (2014) Effect of neuronal nicotinic acetylcholine receptor genes (CHRN) on longitudinal cigarettes per day in adolescents and young adults. Nicotine Tob Res 16:137-44
Mermelstein, Robin J (2014) Adapting to a changing tobacco landscape: research implications for understanding and reducing youth tobacco use. Am J Prev Med 47:S87-9
Piasecki, Thomas M; Trela, Constantine J; Hedeker, Donald et al. (2014) Smoking antecedents: separating between- and within-person effects of tobacco dependence in a multiwave ecological momentary assessment investigation of adolescent smoking. Nicotine Tob Res 16 Suppl 2:S119-26
Sokolovsky, Alexander W; Mermelstein, Robin J; Hedeker, Donald (2014) Factors predicting compliance to ecological momentary assessment among adolescent smokers. Nicotine Tob Res 16:351-8

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